多准则决策分析在孤儿药综合评价中的应用进展

Application Progress of Multi-criteria Decision Analysis in Assessment of Orphan Drugs

多准则决策分析(MCDA)是一个定量、结构化、可用于评估不同准则的决策工具。在孤儿药综合评价过程中,MCDA提供了研究框架和一系列的分析技术,帮助决策者评估干预措施的准则,衡量干预措施在这些准则上的表现,明确相关准则的权重,将表现和优先级数据综合为全面的评价。随着全球孤儿药市场的快速增长,MCDA的应用已成为各国孤儿药价值评估的研究热点之一。笔者通过分析孤儿药临床综合评价的特殊性,详细介绍MCDA应用于孤儿药评价的理论基础,总结了近几年MCDA在孤儿药综合评价中的应用进展,最后对我国未来应用MCDA评估孤儿药价值进行了展望。

Multi-criteria decision analysis(MCDA)is a quantitative,structured,and decision-making tool that can be used to evaluate different criteria.In the process of the comprehensive evaluation of orphan drugs,MCDA provides a research framework and a series of analysis techniques to help decision-makers evaluate criteria for intervention measures,measure the performance of intervention measures on these criteria,clarify the weights of relevant criteria,set performance and priority,and related data is integrated into a comprehensive evaluation.With the rapid growth of the global orphan drug market,the application of MCDA has become one of the research hotspots in the evaluation of the value of orphan drugs in various countries.By analyzing the particularity of the clinical comprehensive evaluation of orphan drugs,the author introduces detailly the theoretical basis of MCDA in the evaluation of orphan drugs and then summarizes the application progress of MCDA in the comprehensive evaluation of orphan drugs in recent years.Finally,the future prospect of applying MCDA to evaluate orphan drugs in China are described in this paper.