男性年龄、液化时间与精子活力的相关性分析

Correlation Analysis of Male Age,Liquefaction Time and Sperm Motility

目的回顾性分析至笔者医院生殖中心行孕前检查的男性精液常规分析报告,探究不同年龄男性精液质量差异以及精液液化时间与精子活力等精液质量指标有无相关性等问题。方法收集并汇总男性精液分析报告1209例,按年龄进行分组,比较各组间精液质量差异;比较液化时间与其他精液质量参数的相关性。结果>40岁组各项精液参数显著下降(P<0.01);液化正常组中,精子活力正常与异常的报告分别有630例和346例,而液化异常组中,分别有129例和104例,差异有统计学意义(P<0.01);液化正常组中pH值<7.2、7.2~7.8及>7.8分别有73、661及11例,液化异常组中则分别有13、180及9例,差异有统计学意义(P<0.05)。结论男性40岁后精液质量显著下降;液化时间与精子活力及pH值具显著相关性。

Objective To retrospectively analyze the semen quality of male patients visiting the Reproductive Center in a hospital for pre-pregnancy check,to explore the differences in semen quality of men of different ages and whether the liquefaction time is related to semen quality indicators such as sperm motility.Methods A total of 1209 male semen analysis reports were gathered together.The cases were divided into different groups according their ages and the differences in semen quality among them were compared.Then several major abnormal indicators like the liquefaction time,sperm motility and pH value were compared.Results Various semen indexes were significantly reduced in the group over 40 years old(P<0.01).There were 630 cases of normal sperm motility and 346 cases of abnormal sperm motility in the normal liquefaction group.While there were 129 and 104 cases of normal and abnormal sperm motility in the abnormal liquefaction group respectively.The difference was statistically significant(P<0.05).Similarly,there were 73,661 and 11 cases in the normal liquefaction group with pH value<7.2,7.2-7.8 and>7.8 respectively,while there were 13,180 and 9 cases in the normal liquefaction group with the pH value<7.2,7.2-7.8 and>7.8 respectively.The difference was also statistically significant(P<0.05).Conclusion Male semen quality declines significantly after 40 years of age.Liquefaction time has a significant correlation with sperm motility and pH value.