糖尿病周围神经病变的危险因素分析

Risk factors analysis of diabetic peripheral neuropathy

目的探讨糖尿病患者发生糖尿病周围神经病变(DPN)的危险因素并讨论护理对策。方法选择2019年3月—2021年2月就诊于医院的124例糖尿病患者中发生DPN的74例患者作为病例组,未发生DPN的50例患者作为对照组,采用单因素和多因素Logistic回归分析糖尿病患者发生DPN的危险因素。结果单因素分析结果显示,年龄、糖尿病病程、体质指数、餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1c)水平是糖尿病患者发生DPN的危险因素(P<0.05);多因素Logistic回归结果分析显示,年龄≥60岁、体质指数≥24、2hPG≥15 mmol/L、HbA1c≥8%、糖尿病病程≥5年是糖尿病患者发生DPN的独立危险因素(P<0.05)。结论糖尿病患者发生DPN与年龄、糖尿病病程、体质指数、2hPG、HbAlc密切相关,针对上述危险因素实施相应的干预措施,有助于降低DPN发生率。

Objective To explore the risk factors of diabetic peripheral neuropathy(DPN) in diabetic patients and discuss nursing countermeasures. Methods From March 2019 to February 2021,74 patients with DPN were selected as the case group and 50 patients without DPN were selected as the control group.Univariate and multivariate Logistic regression were applied to analyze the risk factors of DPN in diabetic patients.Results Univariate analysis showed that age,duration of diabetes,body mass index,2 h postprandial blood glucose(2 hPG),HbA1c level were the risk factors of DPN in diabetic patients(P<0.05).Multivariate Logistic regression analysis showed that age ≥ 60 years old,body mass index≥24,2 hPG≥15 mmol/L,HbA1c≥8% and duration of diabetes ≥ 5 years were independent risk factors of DPN in diabetic patients(P<0.05).Conclusion The incidence of DPN in diabetic patients was closely related to age,course of diabetes,body mass index,2 hPG and HbAlc,corresponding intervention measures for these risk factors can help reduce the incidence of DPN.