摘要
The global spread of SARS-CoV-2 is currently continuing,and the World Health Organization has announced the risk assessment of the viruses as high.In this study,we analyzed virology features of SARS-CoV-2 causing a family cluster outbreak.Among the six family members,five have been laboratory-confirmed infection of SARS-CoV-2 viruses.A total of five SARS-CoV-2 viruses have been isolated from the nasopharyngeal swabs.The complete genome of the viruses exhibited 100%nucleotide identity with each other.Only two nucleotide differences have been observed between genomes of the isolated viruses and the HCoV/Wuhan/IVDC-HB-01/2019 strain.Therefore,SARS-CoV-2 has been confirmed as the causation of the family cluster infections.
基金
A scientific research project of Shanghai Science and Technology Commission“the Epidemiological Study on COVID 19 in Shanghai”(No.20411950100)
A scientific research project of Shanghai Municipal Commission of Health:molecular Epidemiology of Coronavirus in Acute Respiratory Infections in Shanghai(No.201840033)
Three-Year Action Plan of the Shanghai Municipal Government to Strengthen the Construction of public Health System(2020–2022)“Outstanding young talent project”(No.GWV-10.2-YQ03).
