邵氏组方配突三针治疗甲状腺良性结节

Treating Benign Thyroid Nodules with Shao′s Prescription and Tu San Zhen

目的:观察邵氏组方配突三针治疗甲状腺良性结节的临床疗效。方法:180例甲状腺良性结节患者随机平均分为观察组和对照组。观察组给予邵氏组方配突三针,对照组给予左甲状腺素钠,两组患者均治疗两个月。比较两组患者治疗前后中医证候评分、自身抗体水平、甲状腺情况及临床疗效。结果:治疗后,两组患者中医证候评分均低于治疗前,且观察组低于同期对照组,差异均有统计学意义(P<0.05)。治疗后,两组患者血清甲状腺微粒体抗体(thyroid microsomal antibody,TMAb)及甲状腺球蛋白抗体(thyroglobulin antibodies,TGAb)水平显著低于治疗前,观察组以上指标低于同期对照组,差异均有统计学意义(P<0.05)。治疗后,两组患者甲状腺结节体积、数量及直径均显著低于治疗前,观察组以上指标低于同期对照组,差异均有统计学意义(P<0.05)。观察组患者的结节大小疗效和中医证候疗效分别为91.11%、86.67%,对照组分别为46.67%、41.11%,两组比较,差异均有统计学意义(P<0.05)。结论:邵氏组方配突三针治疗甲状腺良性结节疗效显著,可明显降低患者中医证候积分,TGAb、TMAb抗体水平及甲状腺结节体积、数量。

Objective:To explore the therapeutic effect of Shao′s prescription combined with Tu San Zhen on benign thyroid nodules.Methods:180 patients with benign thyroid nodules were randomly divided into the observation group and control group.The observation group was given Shao′s prescription with Tu San Zhen,and the control group was given levothyroxine sodium.Patients in both groups were treated for two months.The TCM symptom score,autoantibody level,and thyroid condition of the two groups before and after treatment were compared,and the curative effect of the two groups was observed.Results:After treatment,the TCM syndrome scores of the two groups of patients were lower than before treatment,and the observation group was lower than the control group during the same period,the difference was statistically significant(P<0.05).After treatment,the serum thyroid microsomal antibody(TMAb)and thyroglobulin antibodies(TGAb)levels of the two groups of patients were significantly lower than those of the control group,and the above indicators in the observation group were lower than those in the observation group during the same period.The differences were statistically significant.Academic significance(P<0.05).After treatment,the volume,number,and diameter of thyroid nodules in the two groups were significantly lower than those in the control group,and the above indicators in the observation group were lower than those in the observation group over the same period,and the differences were statistically significant(P<0.05).The nodule size curative effect and TCM syndrome curative effect of the observation group were 91.11%and 86.67%,respectively,and the control group was 46.67%and 41.11%respectively.The difference between the two groups was statistically significant(P<0.05).Conclusion:Shao′s prescription combined with Tu San Zhen has a significant effect on the treatment of benign thyroid nodules,which can significantly reduce the patient′s TCM syndrome score,the level of TGAb and TMAb antibodies,and the volume and number of thyroid nodules.