铁代谢与心力衰竭关系的研究进展

The Relationship Between Iron Metabolism and Heart Failure

心力衰竭(心衰)是由各种原因导致的心脏疾病的终末阶段,为当今社会常见的严重疾病,具有发病率高和死亡率高的特点。铁是人体必须的微量元素之一,以离子形式存在于肝、脾、肾、心、骨骼肌和脑等组织中,广泛参与人体的多种生理活动,而铁的代谢平衡是维持人体生命活动的重要部分。多项研究发现铁的代谢与心衰存在一定关系,影响心衰患者的疾病进展及预后情况,现就铁代谢与心衰关系的研究进展进行综述,从铁代谢方向为心衰的防治提供新思路。

Heart failure(HF)is the terminal stage of heart disease caused by various causes.It is a common disease in modern society,and has high morbidity and mortality.Iron is one of the essential trace elements in human body.It exists in liver,spleen,kidney,heart,skeletal muscle,brain and other tissues in the form of ions.It is widely involved in various physiological activities of human body,and the iron metabolic balance is an important part of maintaining human life activities.A number of studies have found that there is a certain relationship between iron metabolism and HF,which affects the disease progression and prognosis of patients with HF.This paper reviews the research progress of the relationship between iron metabolism and HF,providing new ideas for the prevention and treatment of HF from the perspective of iron metabolism.