腹腔镜下全子宫加双附件切除术治疗早期子宫内膜癌患者的效果

Effects of laparoscopic total hysterosalpingo-oophorectomy in treatment of patients with early endometrial cancer

目的:观察腹腔镜下全子宫加双附件切除术治疗早期子宫内膜癌患者的效果。方法:选取78例早期子宫内膜癌患者为研究对象,按照随机数字表法分为观察组与对照组各39例。对照组行腹腔镜广泛子宫切除术治疗,观察组行腹腔镜下全子宫加双附件切除术治疗,比较两组手术相关指标(手术时间、术中出血量、术后首次排气时间、住院时间)水平、住院期间并发症发生率和术后2年生存率。结果:观察组手术时间、术后首次排气时间、住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为5.13%(2/39),低于对照组的25.64%(10/39),差异有统计学意义(P<0.05);观察组术后2年生存率为97.44%(38/39),高于对照组的76.92%(30/39),差异有统计学意义(P<0.05)。结论:腹腔镜下全子宫加双附件切除术治疗早期子宫内膜癌患者可缩短手术时间、术后首次排气时间、住院时间,降低术中出血量和并发症发生率,以及提高术后2年生存率,效果优于腹腔镜下广泛全子宫切除术。

Objective:To observe effects of laparoscopic total hysterosalpingo-oophorectomy in treatment of patients with early endometrial cancer.Methods:78 patients with early endometrial cancer were selected as the research objects,and were divided into observation group and control group according to the random number table method,39 cases in each group.The control group underwent laparoscopic radical hysterectomy,while the observation group underwent laparoscopic total hysterosalpingo-oophorectomy.The levels of surgical indicators(operation time,intraoperative blood loss,first postoperative exhaust time,hospitalization time),the incidence of complications during the hospitalization,and the 2-year survival rate after the surgery were compared between the two groups.Results:The operation time,the first postoperative exhaust time,and the hospitalization time of the observation group were shorter than those of the control group;the intraoperative blood loss was lower than that of the control group;and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 5.13%(2/39),which was lower than 25.64%(10/39)in the control group,and the difference was statistically significant(P<0.05).Further,the 2-year survival rate of the observation group was 97.44%(38/39),which was higher than 76.92%(30/39)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Laparoscopic total hysterosalpingo-oophorectomy for the early endometrial cancer patients can shorten the operation time,the first postoperative exhaust time,the hospitalization time,reduce the amount of intraoperative blood loss and the incidence of complications,and improve the 2-year survival rate after the surgery.Moreover,it is superior to laparoscopic radical hysterectomy.