维生素D防治新型冠状病毒肺炎研究进展

Progress in researches on vitamin D in prevention and treatment of coronavirus disease

新型冠状病毒肺炎(COVID-19)的大流行给全球带来了巨大的健康和经济负担,当前任何可以降低其感染和死亡风险的公共卫生措施均具有十分重要的现实意义。维生素D是一种脂溶性维生素,在预防呼吸道系统感染、增强免疫系统、维持心肺功能等方面均有一定作用,其缺乏可能与COVID-19的感染率、病死率和临床症状存在一定相关性。本文从维生素D防治COVID-19的潜在机制开始,结合当前维生素D与COVID-19之间关系的流行病学研究结果以及相关临床证据,对维生素D与COVID-19关系的研究进展进行了综述,旨在为COVID-19的防治提供新的思路。

The coronavirus disease 2019(COVID-19)pandemic has imposed an enormous burden on health and economy around the world.All public health measures that can reduce the risk of infection and death are of great practical importance.Vitamin D is a fat-soluble vitamin,which plays a certain role in preventing respiratory tract infection,enhancing immune system and maintaining cardiopulmonary function,and it’s deficiency may be related to infection rate,case fatality rate and clinical symptoms of COVID-19.In view of this,the study starts with the potential mechanism of vitamin D in the prevention and treatment of COVID-19,combined with current epidemiological research results and relevant clinical evidences on the relationship between vitamin D and COVID-19,and synthesizes current progress in researches on the relationship between vitamin D and COVID-19,to provide new thought for the prevention and treatment of COVID-19.