阻塞型睡眠呼吸暂停低通气综合征与代谢综合征相关性的研究进展

Research progress on the relationship between obstructive sleep apnea hypopnea syndrome and metabolic syndrome

近年来,越来越多的研究显示阻塞型睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)与代谢综合征紧密联系且相互影响,而高血压、糖代谢异常、脂代谢紊乱、肥胖作为代谢综合征的主要组成成分更是被深入研究。持续气道正压通气是目前治疗OSAHS最主要的方法。该文就OSAHS与高血压、糖代谢异常、脂代谢紊乱、肥胖之间的关系及气道正压通气治疗效果进行综述,旨在为OSAHS合并代谢综合征的发病机制及治疗提供理论依据。

In recent years,more and more studies have shown that obstructive sleep apnea hypopnea syndrome(OSAHS)and metabolic syndrome are closely related and interact with each other,while hypertension,abnormal glucose metabolism,lipid metabolism disorders and obesity,as the main components of metabolic syndrome,have been further studied.Continuous positive airway pressure is currently the main treatment for OSAHS.This review focuses on the association between OSAHS and hypertension,glucose metabolism abnormalities,lipid metabolism disorders,obesity and the effects of treatment with positive airway pressure,aiming to provide a theoretical basis for the pathogenesis and treatment of OSAHS complicated with metabolic syndrome.