地佐辛对腹腔镜手术患儿苏醒期躁动的影响

Effect of Dezocine on recovery period agitation in children with laparoscopic surgery

目的探讨地佐辛对腹腔镜手术患儿苏醒期躁动的影响。方法回顾性选取2018年3月至2021年4月南方医科大学顺德医院收治的86例实施腹腔镜疝囊高位结扎手术的患儿作为研究对象,根据麻醉药物的不同分为对照组和观察组,每组各43例。对照组在常规麻醉措施的基础上给予生理盐水,观察组在常规麻醉措施的基础上给予地佐辛。比较两组不同时间点生命体征、苏醒期躁动评分、疼痛评分、拔管时间、麻醉监护时间以及监护后麻醉改良评分。结果术前5 min(T0)、停药时(T1),两组的平均动脉压和心率比较,差异无统计学意义(P>0.05);拔管时(T2)、拔管5 min(T3)时,观察组的平均动脉压和心率低于同期对照组,差异有统计学意义(P<0.05);对照组T1、T2、T3时的平均动脉压和心率高于本组T0时,差异有统计学意义(P<0.05);观察组T1、T2、T3时的平均动脉压高于本组T0时,差异有统计学意义(P<0.05);观察组T1、T2时的心率高于本组T0时,差异有统计学意义(P<0.05);观察组T3时的心率与本组T0时比较,差异无统计学意义(P>0.05)。观察组苏醒期躁动与疼痛评分低于对照组,差异有统计学意义(P<0.05)。两组的拔管时间、监护后麻醉改良评分比较,差异无统计学意义(P>0.05);观察组的麻醉监护时间长于对照组,差异有统计学意义(P<0.05)。结论在腹腔镜疝囊高位结扎手术中注射地佐辛能有效改善患儿全身麻醉后苏醒期躁动的发生率,促进其血流动力学平稳。

Objective To explore the effect of Dezocine on recovery period agitation in children with laparoscopic surgery.Methods A total of 86 children undergoing laparoscopic hernia sac high ligation surgery admitted to Shunde Hospital of Southern Medical University from March 2018 to April 2021 were selected retrospectively as the study subjects,and divided into the control group and the observation group according to the anesthetic drugs different,with 43 cases in each group.The control group administered saline on the basis of conventional anesthesia measures,and the observation group gave Dezocine on the basis of conventional anesthesia measures.The vital signs,agitation scores at different time points,awakening period,pain score,extubation time,anesthesia monitoring time and monitoring anesthesia improvement score were compared between the two groups.Results At 5 min before operation(T0),the time of drug with drawal(T1),the mean arterial pressure and heart rate were compared between the two groups,with no significantly significant differences(P>0.05).At extubation(T2),and 5 min after extubation(T3),the mean arterial pressure and heart rate in the observation group were lower than those in the control group at the same period,and the differences were statistically significant(P<0.05).The mean arterial pressure and heart rate in the control group at T1,T2 and T3 were higher than those at T0 in this group,and the differences were statistically significant(P<0.05).The mean arterial pressure in the observation group at T1,T2 and T3 was higher than that at T0 in this group,and the difference was statistically significant(P<0.05).The heart rate in the observation group at T1 and T2 was higher than that at T0 in this group,and the difference was statistically significant(P<0.05).The heart rate in the observation group at T3 was compared with T0 in this group,with no significantly significant difference(P>0.05).The scores of agitation and pain in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).There were no significant differences in extubation time and anesthesia improvement score between the two groups(P>0.05).The anesthesia monitoring times in the observation group was longer than that in the control group,the difference was statistically significant(P<0.05).Conclusion Injecting Dezocine during laparoscopic high ligation of the hernia sac could effectively improve the incidence of restlessness in children after general anesthesia and promote stable hemodynamics.