早发急性心肌梗死患者的临床及血管病变特点分析

ANALYSIS OF CLINICAL AND CORONARY ARTERY FEATURES OF PREMATURE ACUTE MYOCARDIAL INFARCTION PATIENTS

目的探讨早发急性心肌梗死患者的临床危险因素及血管病变特点。方法 2019年1月—2019年12月于该院因急性心肌梗死性且急诊经皮冠脉介入诊疗的178例患者为研究对象,收集患者的病历资料进行了回顾性分析。根据年龄将入选对象分为早发组(男性<55岁,女性<65岁)44例和晚发组(男性≥55岁,女性≥65岁)134例,比较二组一般资料、临床资料和冠状动脉病变特点。结果早发组及晚发组中高血压所占比例均较高(52.3%vs.67.2%),组间比较差异无统计学意义(P>0.05);早发组体质指数为(26.71±3.03)kg/m^(2),明显高于晚发组(23.99±2.89)kg/m^(2),组间比较差异有统计学意义(P<0.05);早发组甘油三酯水平为(2.14±1.39)mmol/L,明显高于晚发组(1.67±1.06)mmol/L,组间比较差异有统计学意义(P<0.05)。经多因素Logistic分析显示,体质指数和甘油三酯均是早发组的独立危险因素,OR值分别为1.609(95%CI:1.151~2.251)、1.379(95%CI:1.211~1.570);早发组冠脉病变支数明显低于晚发组(2.0±0.86vs.2.43±0.69,P<0.05)。结论体质指数、甘油三酯是早发急性心肌梗死的独立危险因素。早发急性心肌梗死患者冠脉以为单、双支病变为主。

Objective To investigate the risk factors and coronary artery features of PAMI(Premature acute myocardial infarction, PAMI) patients.Methods In this retrospective study, one hundred and seventy-eight patients that had received emergency percutaneous coronary intervention treatment during Jan 2019 to Dec 2019 in the KaiLuan Hospital are selected as study subjects and their inpatient medical records data are analyzed.According to age, study subjects are divided as study group(with male<55 years or female<65 years) and control group(with male≥55 years or female≥65 years).There are 44 subjects in the study group and 134 subjects in the control group.The general data, clinical data and coronary artery features are compared with statistical methods in this study.Results There is a high proportion of hypertension in both study group(52.3%) and control group(67.2%),the difference between groups is not significantly(P>0.05).Body mass index(BMI) of study group average value is(26.71±3.03) kg/m^(2) is significantly(P<0.05) higher than that of control group(23.99±2.89) kg/m^(2).And the triglyceride(TG) of study group(2.14±1.39) mmol/L is significantly higher than that of control group(1.67±1.06) mmol/L(P<0.05).Multivariate logistic analysis shows that both BMI and TG are independent risk factors of PAMI,the OR value is 1.609(95%CI:1.151~2.251)and 1.379(95%CI:1.211~1.570)respectively.The number of stenosed coronary artery in study group(2.0±0.86) is significantly lower than that in control group(2.43±0.69)(P<0.05).Conclusion Both BMI and TG are independent risk factors of PAMI.PAMI patients mainly have single or double coronary artery stenosis.