开喉剑喷雾剂辅助重组人干扰素α–2b雾化治疗HFMD口腔溃疡的效果

Effect of Kaihoujian Spray Assisted with Recombinant Human Interferon α-2b Atomization on HFMD Oral Ulcer

目的:探讨开喉剑喷雾剂辅助重组人干扰素α–2b雾化治疗手足口病(HFMD)口腔溃疡患儿的临床效果。方法:选取2019年1月至2019年11月驻马店市中医院收治的HFMD口腔溃疡患儿129例,均予以对症治疗,在此基础上采取重组人干扰素α–2b雾化治疗的64例为对照组,采取开喉剑喷雾剂辅助重组人干扰素α–2b雾化治疗的65例为观察组。比较两组疗效、康复进程(退热时间、咽痛消失时间、口腔溃疡消失时间、住院时间)。结果:观察组患儿治疗总有效率为96.92 %,高于对照组的78.13 %,差异具有统计学意义(P<0.05);观察组患儿退热时间、咽痛消失时间、口腔溃疡消失时间、住院时间均短于对照组,差异具有统计学意义(P<0.05)。结论:开喉剑喷雾剂辅助重组人干扰素α–2b雾化治疗HFMD口腔溃疡患儿,能缩短患儿康复进程,促进患儿恢复。

Objective To explore the clinical effect of Kaihoujian spray assisted with recombinant human interferon α-2b atomization in the treatment of oral ulcer in children with Hand,foot and mouth disease (HFMD).Methods 129 children with HFMD oral ulcer treated in Zhumadian Hospital of Traditional Chinese Medicine from January 2019 to November 2019 were selected.64 patients in the control group were treated with recombinant human interferon α–2b atomization treatment,65 patients in the observation group were treated with Kaihoujian spray and recombinant human interferon α–2b atomization.The curative effect and rehabilitation process (antipyretic time,disappearance time of pharyngeal pain,disappearance time of oral ulcer and hospitalization time) were compared between the two groups.Results The total effective rate of the observation group was 96.92%,which was higher than 78.13% of the control group (P < 0.05);The fever relief time,pharyngeal pain disappearance time,oral ulcer disappearance time and hospital stay in the observation group were shorter than those in the control group (P < 0.05).Conclusion Kaihoujian spray assisted with recombinant human interferon α–2b atomization in the treatment of children with HFMD oral ulcer,which can shorten the rehabilitation process and promote the recovery of children.