新型纳米硒材料的合成调控及其在生物医学中的应用研究进展

New nano-selenium materials:its synthesis regulation and applications in biomedicine

纳米硒具有易吸收、低毒性、生物活性高等特点,在农业、医疗、生物等领域得到了广泛的应用,但纳米硒不稳定、易聚集、难以回收利用。为了克服这些缺点,研究人员一直致力于探索制备新型纳米硒材料,并深入了解可能的有助于开发新型高效的纳米硒的调控方法。本文主要总结了纳米硒活性调控方法,介绍了近年来纳米硒在生物传感、成像、抗菌、抗病毒、癌症治疗、抗氧化等领域的研究进展,提出了纳米硒材料目前面临的挑战以及未来的研究重点,旨在为纳米硒在营养和临床医学中的应用提供参考。

Nano-selenium(selenium nanoparticles,SeNPs)has been widely used in agriculture,medicine,biology and other fields due to its characteristics of easy absorption,low toxicity,and high biological activity,etc..However,SeNPs are unstable,easy to aggregate,and difficult to recycle.To overcome these shortcomings,researchers have been devoted to exploring the new methods of preparation and regulation of nano-selenium materials.This article mainly summarizes the methods of regulating the activity of nano-selenium materials and introduces their applications in the fields of biosensing,imaging,anti-bacteria,anti-virus,cancer therapy,and anti-oxidation.Furthermore,the current challenges and future perspectives are proposed.It will provide references for understanding the properties of nano-selenium and developing functionalized nano-selenium food.