期刊文献+

慢性心力衰竭合并低T3综合征的预后分析 被引量:5

下载PDF
导出
摘要 目的探讨低T3综合征在评估慢性心力衰竭患者预后的作用。方法130例慢性心力衰竭(NYHAⅡ~Ⅳ级)患者,根据入院后2~5 d内检测游离的T3水平分为慢性心力衰竭合并低T3综合征组(n=42)和慢性心力衰竭不合并低T3综合征组(n=88),分析两组一般临床资料以及心脏功能参数。出院后随访(5.02±1.58)个月,记录患者再次入院或死亡事件。结果两组患者在年龄、糖尿病、NYHA分级、左心室横径、NT-proBNP值、血红蛋白、室性心动过速、FT3值有统计学差异(P<0.05)。Logistic多因素回归分析显示,高龄、合并糖尿病、高NYHA分级和低FT3水平是慢性心力衰竭患者再住院或死亡的独立危险因素。通过Kaplan-Meier分析,低T3综合征患者出院后复合终点(死亡或再次入院)发生率明显高于T3水平正常的患者(P=0.000),而生存分析亚组中低T3综合征的生存率也明显低于T3水平正常组(P=0.000)。结论低T3水平是慢性心力衰竭患者预后不良的独立预测指标,可作为心衰患者评估临床预后的重要指标之一。
出处 《贵州医药》 CAS 2022年第1期86-88,共3页 Guizhou Medical Journal
  • 相关文献

参考文献2

二级参考文献35

  • 1Adler SM, Wartofsky L. The nonthyroidal illness syndrome. Endo- crinolM etab Clin North Am,2007,36: 657-672.
  • 2ESC committee for practice guidelines. ESC guidelines for the di- agnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiolo- gy. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail,2012,14 : 803-69.
  • 3Ascheim DD, Hryniewicz K. Thyroid hormone metabolism in pa- tients with congestive heart failure : the low triiodothyronine state. Thyroid,2002,12 : 511-515.
  • 4成人体重判定.中华人民共和国国家卫生与计划生育委员会.罗越,吴艺捷.碘化甲腺原氨酸脱碘酶的研究进展.国际内分泌代谢杂志,2004,4:53-55.
  • 5Galli E, Pingitore A, Iervasi G. The role of thyroid holTnone in the pathophysiology of heart failure: clinical evidence. Heart Fail Rev,2010,15 : 155-169.
  • 6Tognini S, Marchini F, Dardano A, et al. Nonthyroidal illness syndrome and short-term survival in a hospitalised older popula- tion. Age Ageing,2010,39 : 46-50.
  • 7D'Moia A,Vizzardi E,Bugatti S,et al. Effect of short-term infusive dobutamine therapy on thyroid hormone profile and hemodynamic pa- rameters in patients with acute worsening heart failure and low-triio- dothyronine syndrome. Investig Med ,2012,60:907-910.
  • 8Opasich C, Pacini F, Ambrosino N, et al. Sick euthyroid syn- drome in patients with moderate-to-severe chronic heart failure. Eur Heart J, 1996,17 : 1860-1866.
  • 9Perna E,Bangher MC,Macin SM,et al. Thyroid hormones abnor- malities in decompansated heart failure: prognosis of sick euthy- roid syndrome. Eur J Heart Fail,2000,2(Suppl. 1 ) :91.
  • 10Galli E, Pingitore A, Iervasi G. The role of thyroid hormone in the pathophysiology of heart failure : clinical evidence. Heart Fail Rev,2010,15:155-169.

共引文献12

同被引文献57

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部