摘要
目的:探讨基因重组牛碱性成纤维细胞生长因子(rbFGF)促进烧伤创面愈合的临床效果。方法:将2019年7月至2021年4月湛江中心人民医院收治的烧伤患者60例作为研究对象,根据随机数字表法分为观察组与对照组,各30例。对照组接受清创后无菌凡士林纱布外敷治疗,观察组接受清创后rbFGF治疗,对患者治疗1周、2周、3周后的愈合率、总愈合时间、浅Ⅱ度创面愈合时间、深Ⅱ度创面愈合时间情况、治疗3周后的总有效率进行观察。结果:与对照组患者相比,观察组治疗1周、2周、3周的愈合率、治疗3周后的总有效率明显较高,总愈合时间、浅Ⅱ度创面愈合时间、深Ⅱ度创面愈合时间明显较短,差异均具有统计学意义(P<0.05)。结论:rbFGF对促进烧伤创面愈合具有良好的效果。
Objective To investigate the clinical effect of genetic recombined bovine basic fibroblast growth factor(rbFGF)in promoting burn wound healing.Methods 60 burn patients admitted to Central People's Hospital of Zhanjiang from July 2019 to April 2021 were selected as the research objects.According to the random number table method,they were divided into observation group and control group,with 30 cases in each group.The control group received external application of sterile Vaseline gauze after debridement,and the observation group received rbFGF after debridement.The healing rate,total healing time,superficial second degree wound healing time,and deep second degree wound healing time after 1 week,2 weeks,and 3 weeks were observed the total effective rate after 3 weeks of treatment was also observed.Results Compared with the control group,the healing rate of the observation group at 1 week,2 weeks and 3 weeks and the total effective rate after 3 weeks were significantly higher,and the total healing time,shallow second degree wound healing time and deep second degree wound healing time were significantly shorter in the observation group,the differences were all statistically significant(P<0.05).Conclusion rbFGF has a good effect on promoting burn wound healing.
作者
李真树
陈海洲
易梅
LI Zhen-shu;CHEN Hai-zhou;YI Mei(Central People's Hospital of Zhanjiang,Guangdong Zhanjiang 524045)
出处
《深圳中西医结合杂志》
2021年第21期124-126,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine