消化内镜在急性非静脉曲张性上消化道出血治疗中的应用

Application of Digestive Endoscopy in the Treatment of Acute Non-Varicose Upper Gastrointestinal Bleeding

目的:分析消化内镜技术在治疗急性非静脉曲张性上消化道出血(ANVUGIB)的临床效果及安全性。方法:选择娄底市中心医院2019年1月至2020年12月收治的ANVUGIB患者共80例,数字表随机分为保守组和内镜组,每组40例。保守组患者给予常规药物治疗,内镜组患者在此常规药物治疗基础上给予消化内镜技术治疗。比较两组患者的出血阻断时间、住院时间、治疗前后患者血红蛋白水平、血氧饱和度水平、动脉血氧分压(PaO_(2))水平、急性生理与慢性健康评分、治疗总有效率、再出血发生率和不良反应发生情况。结果:内镜组患者的出血阻断时间、住院时间短于保守组,差异具有统计学意义(P<0.05)。治疗后内镜组患者血红蛋白水平、血氧饱和度、PaO_(2)高于保守组,急性生理与慢性健康评分显著低于保守组,差异具有统计学意义(P<0.05)。内镜组患者治疗总有效率为100.00%,高于保守组的80.00%,差异具有统计学意义(P<0.05)。内镜组患者再出血发生率为0.00%,低于保守组的17.50%,差异具有统计学意义(P<0.05)。两组患者均未出现不良反应情况。结论:消化内镜技术治疗ANVUGIB的临床效果确切,可加速出血阻断,维持患者机体健康,并减少再出血的现象,安全性高。

Objective To analyze the clinical efficacy and safety of digestive endoscopy in the treatment of acute non-varicose upper gastrointestinal bleeding(ANVUGIB).Methods A total of 80 ANVUGIB patients admitted to Loudi Central Hospital from January 2019 to December 2020 were selected and randomly divided into conservative group and endoscopic group with 40 patients in each group.The conservative group was treated with conventional drug therapy,and the endoscopic group was treated with digestive endoscopy on the basis of conventional drug therapy.The time of hemorrhage occlusion,length of hospital stay,hemoglobin level,oxygen saturation level,oxygen partial pressure level,acute physiology and chronic health score,total treatment response rate,incidence of rebleeding and adverse reactions were compared between the two groups.Results The bleeding blocking time and hospital stay in the endoscopic group were shorter than those in the conservative group,the differences were statistically significant(P<0.05).After treatment,the level of hemoglobin,oxygen saturation and oxygen partial pressure(PaO_(2))in the endoscopic group were higher than those in the conservative group,and the acute physiological and chronic health scores were significantly lower than those in the conservative group,with statistical significance(P<0.05).The total effective rate of the endoscopic group was 100.00%,higher than 80.00%of the conservative group,the difference was statistically significant(P<0.05).The incidence of rebleeding in the endoscopic group was 0.00%,lower than 17.50%in the conservative group,and the difference was statistically significant(P<0.05).No adverse reactions occurred in the two groups.Conclusion The clinical effect of digestive endoscopy in the treatment of ANVUGIB is definite,which can accelerate the blocking of bleeding,maintain the health of patients,and reduce the phenomenon of rebleeding,with high safety.