摘要
吡非尼酮是一种新的广谱抗炎及抗纤维化药物,尤其对治疗特发性肺纤维化具有非常好的效果。但同时也存在较大的毒副作用,如光过敏。本文报道1例肺纤维化患者服用吡非尼酮4周后出现严重光毒性反应,停用吡非尼酮并给予糖皮质激素治疗后,皮损逐渐消退。
Pirfenidone is a new broad-spectrum anti-inflammatory and anti-fibrosis drug, which has a very good effect on idiopathic pulmonary fibrosis. But it also has more adverse reactions, such as photosensitivity. We report a case of pulmonary fibrosis with severe phototoxicity after 4 weeks of pirfenidone treatment in this paper. The skin lesions gradually subside after pirfenidone was discontinued and glucocorticoid was given.
作者
李隽
张理涛
LI Jun;ZHANG Litao(Tianjin University of Traditional Chinese Medicin,Tianjin 301617,China;Department of Dermatology,Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital,Tianjin 300120,China)
出处
《中国麻风皮肤病杂志》
2022年第4期236-237,共2页
China Journal of Leprosy and Skin Diseases
