希望水平在晚期肺癌患者抑郁状态与心理韧性中的中介效应

Mediating effect of hope level between depression and psychological resilience in patients with advanced lung cancer

目的探讨希望水平在晚期肺癌患者抑郁与心理韧性水平的中介效应,为临床医护人员开展心理韧性相关干预,改善患者抑郁状态提供理论依据。方法采用便利抽样法选取2019年10月至2020年12月在北京协和医院肺癌诊治中心接受规律治疗的202例肺癌患者为研究对象。应用Herth希望量表、心理韧性量表(CD-RISC)、抑郁自评量表(SDS)以及自行设计的患者人口学特征和疾病特征资料调查表对患者进行问卷调查。结果晚期肺癌患者抑郁水平与患者心理韧性呈负相关(r=-0.50,P<0.01),患者希望水平与心理韧性呈正相关(r=0.62,P<0.01),患者抑郁水平与希望水平呈负相关(r=-0.44,P<0.01);晚期肺癌患者希望水平在抑郁状态与心理韧性中存在部分中介效应,中介效应值为-16.51(95%CI=-0.20~-0.03),中介效应占比为19.83%。结论接受规律治疗的晚期肺癌患者抑郁程度较高,希望在抑郁状态和心理韧性之间起到部分中介效应。医护人员可通过干预提升晚期肺癌患者的信心和希望,改善悲观情绪。

Objective To explore the mediating effect of hope level in the depression and psychological resilience of patients with advanced lung cancer,in order to provide a theoretical basis for interventions to improve the depression state of patients.Methods Across-sectional survey was conducted in 202 patients with advanced lung cancer who were admitted to the Department of Respiratory Medicine of PUMCH from October 2019 to December 2020,using the Herth Hope Scale,Connor-Davidson resilience scale(CD-RISC)and a self-designed questionnaire on patient general condition and disease characteristics.Results The depression level of patients with advanced lung cancer was negatively correlated with the psychological resilience of the patients(r=-0.50,P<0.01).The hope level of the patients was positively correlated with the psychological resilience(r=0.62,P<0.01).The depression level of the patients was negatively correlated with the hope level(r=-0.44,P<0.01).The level of hope of patients with advanced lung cancer has a partial mediating effect in depression and mental resilience.The mediating effect value is-16.51(95%CI=-0.20~-0.03),the ratio is 19.83%.Conclusions Patients with advanced lung cancer who receive regular treatment have a higher degree of depression,and the hope level play a role of the mediating effect between depression and mental toughness.Medical staff should improve the confidence and hope of patients with advanced lung cancer through intervention,and improve pessimism.