脑梗死后血管性认知障碍的危险因素研究进展

Research Progress on Risk Factors of Vascular Cognitive Impairment after Cerebral Infarction

脑梗死后血管性认知障碍(Vascular cognitive impairment,VCI)的致病率越来越高,目前研究未能明确该病的发病机制,可能与患者的血压、年龄、基础疾病、血清生物标志物及炎症等相关因素有密切联系,导致临床上还没有药物可以阻止或逆转痴呆症的发展,严重影响患者的生活质量,甚至给家庭和社会带来沉重的负担。故文章探讨脑梗死后VCI的危险因素对其发病机制、治疗及预防具有重要的临床意义,为预防VCI和阻止其发展为血管性痴呆提供临床依据。

The incidence of vascular cognitive impairment(VCI) after cerebral infarction is getting higher and higher. At present,studies have failed to clarify the pathogenesis of the disease, which may be closely related to the patient’s blood pressure, age, basic diseases,serum biomarkers, inflammation and other related factors, resulting in no drugs to prevent or reverse the development of dementia. It seriously affects the quality of life of patients, and even brings a heavy burden to families and society. Therefore, to explore the risk factors of VCI after cerebral infarction has important clinical significance for its pathogenesis, treatment and prevention, so as to provide clinical basis for preventing VCI and preventing its development and vascular dementia.