某院常用静脉用药浓度不合理医嘱原因分析

The causes of unreasonable intravenous medicine concentration of prescriptions in our hospital

目的根据某院静脉药物终浓度不合理医嘱,提出干预措施,为临床合理用药提供参考。方法收集整理2020年7月~2021年6月某院静配中心静脉药物终浓度不合理医嘱,分析具体原因。结果常见浓度不合理医嘱以电解质类、抗生素类、抗肿瘤药物为主,分别占23.79%、20.19%、11.64%,与药物溶解不完全、增加不良反应及不能达到有效浓度等有关。结论临床应根据药物理化性质,合理配置静脉药物终浓度,更好为患者提供药学服务。

Objective According to the unreasonable medical advice of the final concentration of intravenous drugs in a hospital,the intervention measures were put forward to provide reference for clinical rational drug use.Methods Collect and sort out the unreasonable medical orders of the final concentration of intravenous drugs in the intravenous distribution center of a hospital from July 2020 to June 2021,and analyze the specific reasons.Results The common medical orders with unreasonable concentration are mainly electrolytes,antibiotics and antitumor drugs,accounting for 23.79%,20.19%and 11.64%respectively,which are related to incomplete dissolution of drugs,increased adverse reactions and failure to reach effective concentration.Conclusion According to the physicochemical properties of drugs,the final concentration of intravenous drugs should be reasonably configured to better provide pharmaceutical care for clinical and patients.