小柴胡汤加减治疗流行性感冒效果观察

Effect observation of Xiaochaihu decoction in the treatment of influenza

目的:在流行性感冒治疗中应用小柴胡汤加减治疗,并分析其临床疗效。方法:选取2017年1月-2020年1月,在淄博市市级机关医院治疗的80例流行性感冒患者,采取随机数字表法,将其分为观察组和对照组两组。其中对照组为40例,采取常规西医治疗,使用复方氨酚烷胺片(口服,1片/次,2次/d),部分患者联合使用布洛芬;观察组40例观察组患者采取小柴胡汤加减治疗,药方组成:柴胡12 g,半夏10 g,党参10 g,黄芩3 g,甘草5 g,生姜10 g,大枣10 g,桔梗10 g,防风10 g,荆芥10 g,在此基础上辨证加减,若为偏风寒者,加桂枝15 g;若为偏风热者,加连翘15 g,金银花15~20 g,两组患者均3 d为1个疗程,治疗1~2个疗程。对比两组患者的临床疗效及完全退热时间、临床痊愈时间。结果:观察组患者的总有效率为95.0%(38/40),对照组为77.5%(31/40),差异有统计学意义(χ^(2)=5.16,P<0.05);治疗后,观察组患者的完全退热、临床痊愈时间分别为(34.34±2.43)h、(55.38±3.23)h,对照组患者分别为(60.61±2.17)h、(80.75±11.92)h,观察组各时间均明显短于对照组(t=50.998、13.777,P<0.05)。结论:小柴胡汤具有疏泄肝胆、健脾和胃、清热利湿、扶正祛邪的功能。对流行性感冒患者应用小柴胡汤加减治疗可获得更加理想的治疗效果,同时可缩短病程,与常规西药相比具有一定优势。

Objective:To apply Xiaochaihu decoction(小柴胡汤)in the treatment of influenza,and analyze its clinical efficacy.Methods:80 patients with influenza treated in Zibo Municipal Government Hospital of Traditional Chinese Medicine from January 2017 to January 2020 were selected and divided into the observation group and the control group by random number table method.In the control group,40 patients were treated with conventional western medicine.Compound aminophenamine tablets(oral,1 tablet/time,2 times/d)were used.Some patients were given ibuprofen in combination.The 40 patients in the observation group were treated with Modified Xiaochaihu decoction.The prescription composition was as follows:Chaihu(bupleurum)12 g,Banxia(pinellia ternata)10g,Dangshen(codonopsis)10 g,scutellaria 3 g,liquorice 5g,ginger 10 g,jujube 10g,platycodon 10g,parsnip 10g,schizonepeta 10g.For those with windward fever,15 g forsythia and 15~20 g honeysuckle were added.Patients in both groups were given one course of treatment of 3 days,with 1~2 courses of treatment.The clinical efficacy,time of complete fever reduction and time of clinical recovery were compared between the two groups.Results:The total effective rate in the observation group was 95%(27 cases showed significant effect,11 cases showed improvement)and 77.5%in the control group(23 cases showed improvement,8 cases showed improvement),which was with significant difference(χ^(2)=5.16,P<0.05).After treatment,the total fever reduction and clinical recovery time in the observation group were(34.34±2.43)h and(55.38±3.23)h,respectively,and those in the control group were(60.61±2.17)h and(80.75±11.92)h,respectively,which were significantly shorter in the observation group than those in the control group(t=50.998,13.777,P<0.05).Conclusion:Xiaochaihu decoction has the functions of relieving liver and gallbladder,strengthening spleen and stomach,clearing away heat and dampness,and nourishing health and dispelling pathogenic factors.Xiaochaihu decoction has more ideal therapeutic effect in the treatment of influenza of patients,at the same time,it can shorten the course of disease and has a certain advantage compared with conventional western medicine.