摘要
生殖器疱疹是一种临床上常见的性传播疾病之一,主要由单纯疱疹病毒(herpes simplex virus, HSV)感染引起。本病临床特征是易反复发作,皮损常伴明显疼痛,对患者的心理造成较大影响,降低了患者生活的质量。干扰素是由多种细胞产生的具有抗病毒、抗肿瘤和免疫调节等多种生理功能的可溶性糖蛋白,临床上可用于复发性生殖器疱疹(recurrent genital herpes, RGH)的治疗,安全性较好,使用方便。本文分别从复发性生殖器疱疹的临床特点、发病机制、治疗方案选择及干扰素在复发性生殖器疱疹中的应用等方面做一简述。
Genital herpes is a common sexually transmitted disease mainly caused by herpes simplex virus infection.The disease is characterized by the repeating recurrences with obvious pain, which impact the psychological health and quality of life of the patients.Interferon is a soluble glycoprotein produced by a variety of cells with antiviral, anti-tumor and immunomodulatory effects.Clinically, it can be used in the treatment of recurrent genital herpes with the advantage of good safety and convenience.This article provides an overview of clinical characteristics, pathogenesis, therapeutic options and application of interferon therapy for recurrent genital herpes.
作者
刘薇
李珊山
LIU Wei;LI Shanshan(Department of Dermatology and Venerology,First Hospital of Jilin University,Changchun 130021,China)
出处
《皮肤科学通报》
2021年第6期538-542,共5页
Dermatology Bulletin
关键词
复发性生殖器疱疹
干扰素
临床治疗
研究进展
Recurrent genital herpes
Interferon
Clinical treatment
Research progress
