期刊文献+

干扰素治疗带状疱疹的用药策略 被引量:3

Interferon in the Treatment of Herpes Zoster
下载PDF
导出
摘要 带状疱疹是由水痘-带状疱疹病毒感染引起的病毒性皮肤病。临床常见,起病急,尤其是年龄大的患者,病情较重,出现合并症及带状疱疹后遗神经痛的概率较高,给患者健康及生活质量带来极大的影响。目前治疗方案以抗病毒、止痛为主,但是单一用药有局限性,更多主张联合用药。干扰素是具有多种生物学功能的糖蛋白,在治疗病毒感染性皮肤病方面有卓越的疗效,本文就干扰素在治疗带状疱疹中的应用及安全性进行总结和讨论。 Herpes zoster is a viral skin disease caused by varicella zoster virus infection.It is more common in clinic and has an acute onset, especially in older patients.The incidence rate of complications and postherpetic neuralgia are high, which has a great impact on the health and quality of life of patients.At present, the treatment strategy is mainly antiviral and analgesic, though single drug use has limitations, so the combined drugs are more recommended.Interferon is a glycoprotein with multiple biological functions and has excellent curative effect in the treatment of viral infectious skin diseases.It will be summarized and discussed about the effectiveness and safety of interferon in the treatment of herpes zoster in this paper.
作者 张燕飞 ZHANG Yanfei(Department of Dermatology,the Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,China)
出处 《皮肤科学通报》 2021年第6期543-547,共5页 Dermatology Bulletin
关键词 带状疱疹 干扰素 疗效 安全性 Herpes zoster Interferon Effective Safety
  • 相关文献

参考文献5

二级参考文献40

  • 1李德敏,林树新.大鼠脑室注射α干扰素增强脾交感神经活动[J].第四军医大学学报,1997,18(3):238-240. 被引量:6
  • 2Decosterd I,Woolf CJ.Spared nerve injury:an animal model of persistent peripheral neuropathic pain[J].Pain,2000,87(2):149-158.
  • 3Zhu QZ,Zhang XB,Wang J,et al.Human IFN-α analgesic role relating to opiate receptor[J].Clin J Appl Rhysiol,1997,14:372-375.
  • 4Zimmerman M.Ethical guidelines for investigations of experimental pain in conscious animals[J].Pain,1983,16(2):109-110.
  • 5Jasmin L,Kohan L,Franssen M,et al.The cold plate as a test of nocieceptive behavirors:description and application to the study of chronic neuropathic and inflammation pain models[J].Pain,1998,75:367-372.
  • 6Chaplan SR,Bach FW,Pogrel JW,et al.Quantitative assessment of tactile allodynia in the rat paw[J].J Neuroscience Methods,1994,53:55-63.
  • 7Dixon WJ.Efficient analysis of experimental observations[J].Ann Rev Pharmacol Toxicol,1980,20:441-462.
  • 8Carlforsj D, Rheological H. Evaluation and ocular comtact time of some carbomer gals for opthalmit use int[ J]. J Pharm, 2012, 137(2) : 333-334.
  • 9Lo J, Hurta RA. Over-expression of K-FGF or bFEF results in altered expression of matrix metalloproteinases: corrletions with malignat progression and cellular and cellular invasion [ J ]. Cell Biollnt, 2012, 26(4) : 319-320.
  • 10戴子娴,张宏,林妙英,梁肖云.更昔洛韦眼用凝胶治疗上皮型单纯疱疹病毒性角膜炎临床疗效观察[J].亚太传统医药,2009,5(7):100-101. 被引量:18

共引文献40

同被引文献66

引证文献3

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部