山西省长治市潞城区2018年至2020年子宫颈癌筛查情况分析

Analysis of the situation of cervical cancer screening from 2018 to 2020 in Lucheng District of Changzhi City,Shanxi Province

目的分析山西省长治市潞城区2018年至2020年免费子宫颈癌筛查情况。方法回顾性分析2018年至2020年在山西省长治市潞城区妇幼保健计划生育服务中心进行免费子宫颈癌筛查的13043例女性子宫颈液基薄层细胞学检查(TCT)结果,TCT阳性者行阴道镜检查和活组织病理检查。结果13043例女性中,TCT筛查阳性800例,阳性率为61.3/10万。2018年、2019年、2020年子宫颈癌筛查TCT阳性率分别为4.82%(145/3006)、5.63%(170/3017)、6.91%(485/7020),呈逐年上升趋势(列联系数=0.037)。2018年、2019年、2020年35~44岁女性TCT阳性率分别为2.95%(31/1052)、3.78%(42/1112)、4.22%(83/1969),45~54岁女性分别为5.48%(68/1241)、6.50%(90/1385)、7.72%(2258/3341),55~64岁女性分别为6.45%(46/713)、7.31%(38/520)、8.42%(144/1710);同一年不同年龄段间、不同年相同年龄段间及3年整体不同年龄段间子宫颈癌筛查TCT阳性率差异均有统计学意义(均P<0.05),年龄为45~54岁、55~64岁女性子宫颈癌筛查TCT阳性率较年龄35~44岁高(均P<0.05)。800例子宫颈癌筛查TCT阳性者中,确诊子宫颈上皮内瘤变(CIN)615例(76.9%),CIN发病率为4.72%(615/13043);不同年份CIN发病率差异有统计学意义(P<0.05)。结论山西省长治市潞城区2018年至2020年子宫颈癌筛查阳性率逐年上升,早期进行子宫颈癌筛查可及时发现子宫颈病变。

Objective To analyze the situation of free cervical cancer screening from 2018 to 2020 in Lucheng District of Changzhi City,Shanxi Province.Methods The cervical liquid-based thin-layer cytology(TCT)results of 13043 women who underwent free cervical cancer screening at the Lucheng District Maternal and Child Health Family Planning Service Center of Changzhi City in Shanxi Province from 2018 to 2020 were retrospectively analyzed.The women with positive TCT results underwent colposcopy and biopsy.Results Among 13043 women,800 women were positive for TCT,with a positive rate of 61.3/100000.The positive rates of cervical cancer screening TCT in 2018,2019 and 2020 were 4.82%(145/3006),5.63%(170/3017)and 6.91%(485/7020),which showed an upward trend year by year(contingency coefficient=0.037).In 2018,2019 and 2020,the positive rates of TCT among women aged 35-44 years old were 2.95%(31/1052),3.78%(42/1112)and 4.22%(82/1969),among women aged 45-54 years old were 5.48%(68/1241),6.50%(90/1385)and 7.72%(2258/3341),and among women aged 55-64 years old were 6.45%(46/713),7.31%(38/520)and 8.42%(144/1710);the positive rates of cervical cancer screening TCT among different age groups in the same year,same age group in different years and overall different age groups in 3 years were statistically significant(all P<0.05),and the positive rates of cervical cancer screening TCT in women aged 45-54 and 55-64 years old were higher than those in women aged 35-44 years old(all P<0.05).Among 800 cases of positive cervical cancer screening TCT,615 cases(76.9%)were diagnosed with cervical intraepithelial neoplasia(CIN),and the incidence rate of CIN was 4.72%(615/13043);there was statistical differences in the incidence of CIN among different years(P<0.05).Conclusions The positive rates of cervical cancer screening increase year by year from 2018 to 2020 in Lucheng District of Changzhi City,Shanxi Province.Early cervical cancer screening can detect cervical lesions in time.