腹腔积液在卵巢癌诊治中的研究进展

Progress of ascites in diagnosis and treatment of ovarian cancer

卵巢癌起病隐匿,确诊时多为中晚期,多伴有腹腔积液,在妇科恶性肿瘤中预后最差。腹腔积液是腹腔内液体的病理积聚,包含多种细胞成分和非细胞成分,促进肿瘤转移,导致化疗耐药,严重影响患者生命质量和预后。现对卵巢癌腹腔积液的基本特性及近年来在诊治中的新进展进行综述,为进一步的研究提供参考。

Owing to its insidious onset,the diagnosis of ovarian cancer is usually delayed and followed with ascites,which results in a poor prognosis compared to other gynecological malignant tumors.Ascites,a pathological accumulation of fluid in the abdominal cavity,contains a variety of cellular and non-cellular components,which promotes tumor metastasis,leads to chemotherapy resistance,and seriously affects the quality of life and prognosis of patients.In this article,the basic characteristics and the recent progress of ascites in ovarian cancer are reviewed,so as to provide references for further research.