离子迁移谱技术的应用发展前景

Prospects of Ion Mobility Spectrometry Applications

新时期国际反恐防暴形势严峻,重大特大工业生产环境污染事故时有发生,国家人民面临着化学战剂(Chemical Warfare Agents,CWAs)和工业有毒化学品(Toxic Industrial Chemicals,TICs)等化学毒剂的威胁是不争的事实。实时快速检测分析环境中化学毒剂和有害气体物质是制定疏散和防护策略、避免次生灾害、减少人员伤害、消除社会恐慌的前提。离子迁移谱(Ion Mobility Spectrometry,IMS)技术恰好顺应了这个趋势,它从20世纪70年代发展至今,被普遍应用于测定痕量的化学物品,毒品,爆炸物,以及空气污染物等物质的分析检测。是一种前景广泛的化学分析检测技术之一,已经在很多领域获得了快速发展和广泛应用。主要简要介绍了IMS中的关键技术研究进展,论述了IMS离子从检测到分析的基本过程的设计中的关键技术点。希望为以后IMS技术商业化应用仪器研制提供参考资料。

In the new era,the international anti-terrorism and riot control situation is severe,major industrial production and environmental pollution accidents occur from time to time,and it is an indisputable fact that the people of the country are facing the threat of chemical warfare agents(CWAs)and toxic industrial chemicals(TICs)and other chemical agents.Real-time and rapid detection and analysis of chemical agents and hazardous gas substances in the environment is a prerequisite for developing evacuation and protection strategies,avoiding secondary disasters,reducing human injuries,and eliminating social panic.Ion Mobility Spectrometry(IMS)has been developed from the 1970 s to the present day and is commonly used to determine trace amounts of chemicals,drugs,explosives,and air pollutants.It is one of the most promising techniques for chemical analysis and has gained rapid development and wide application in many fields.The key technology research progress in IMS is briefly introduced,and the key technology points in the design of the basic process of IMS ion from detection to analysis are discussed.It is hoped that this will provide reference material for future instrument development for commercial application of IMS technology.