摘要
目的应用3D-STI评估HCM患者左心室早期局部收缩功能障碍。方法心脏超声检查诊断的肥厚型心肌病患者为肥厚型心肌病组(HCM组)共35例,非梗阻型(NHCM)19例,梗阻型(OHCM)16例,同时收纳体检者30例为对照组(NOR),3D-STI技术测量3组样本左心室16节段径向应变(RS)、纵向应变(LS)、圆周应变(CS)进行比较。结果与NOR组比较,NHCM组、OHCM组病例组的常规二维指标IVSD、LVPWD、LVMI、LVOT-PG增加明显(P<0.05);与NHCM组比较,OHCM组样本的IVSD、LVPWD以及LVOT-PG增加显著(P<0.05);与NOR组比较,NHCM组、OHCM组病例组大部分节段LS明显减低(P<0.05);与NHCM组比较,OHCM组的后间隔及前壁基底段LS显著降低(P<0.05);与NOR组比较,NHCM组、OHCM组病例组室间隔基底段、中段以及前、下壁基底段RS显著降低(P<0.05),其余各节段的RS虽有降低趋势但差异无统计学意义(P>0.05);与NOR组比较,NHCM组、OHCM组前间隔基底段CS显著降低(P<0.05),侧壁基底段CS显著增加(P<0.05)。结论3D-STI技术所获得HCM患者的左心室16节段LS及RS能够准确评价患者早期左心室局部收缩功能的改变,以期为临床提供早期诊断及早期干预的可靠依据。
Objective To explore the left ventricular regional systolic function in early stage of the patients with HCM by 3D-STI.Methods Thirty five patients were selected in the study,including 19 patients with non-obstructive hypertrophic myocardium(NHCM),16 patients with obstructive hypertrophic cardiomyopathy(OHCM);thirty cases of healthy physical examination volunteers were selected as normal control group(NOR).The LV regional longitudinal strain(LS),regional radial strain(RS),regional circumference strain(CS)was measured by 3D-STI,the differences among three groups were compared.Results The IVSD,LVPW,LVOT-PG and LVMI in the two HCM groups were significantly higher than those in NOR group(P<0.05).Compared with NHCM group,the IVSD,LVPW,LVOT-PG in OHCM group were significantly higher than those in the NOR group(P<0.05);The segment LS in the two HCM groups were lower than those in the NOR group(P<0.05).Compared with the NHCM group,the LS in IVS of the OHCM group were significantly decreased(P<0.05);The RS of the basal IVS,the apex IVS,the basal LVAW and the basal LVLW in the two HCM groups were lower than those in the NOR group(P<0.05);The CS of the basal IVS in the two HCM groups were lower than those in the NOR group(P<0.05),the basal LVLW was significantly increased(P<0.05).Conclusion The LV systolic and diastolic functions are damaged,even with a normal LVEF.LV systolic dysfunction impairment in HCM patients can be sensitively revealed by 3D-STI.3D-STI can be provided important information for early diagnosis and prevention.
作者
黄璇
纳丽莎
潘璐
王婷婷
周丽
吴丹
HUANG Xuan;NA Lisha;PAN Lu;WANG Tingting;ZHOU Li;WU Dan(Department of Cardiac Functions Examination Heart Center,General Hospital of Ningxia Medical University,Yinchuan 750004,China)
出处
《宁夏医学杂志》
CAS
2022年第1期18-22,共5页
Ningxia Medical Journal
基金
国家自然科学基金项目(81760318)。
关键词
肥厚型心肌病
三维斑点追踪成像
左心室局部收缩功能
Hypertrophic cardiomyopathy
Three-dimensional speckle tracking imaging
Left ventricle regional systolic function