短时多次蓝光照射治疗新生儿黄疸的效果观察

Observation on effect of short-term multiple blue light irradiation on neonatal jaundice

目的探究新生儿黄疸使用短时多次蓝光照射治疗的临床效果。方法74例新生儿黄疸患儿,采用随机数字表法分为对照组和观察组,各37例。对照组患儿接受长时连续蓝光照射治疗,观察组患儿接受短时多次蓝光照射治疗。对比两组治疗效果、治疗后不良反应发生率,治疗前及治疗后48、72 h血清总胆红素水平。结果观察组患儿治疗总有效率为94.59%,高于对照组的78.38%,差异有统计学意义(P<0.05)。治疗前及治疗后48 h,两组患儿血清总胆红素水平比较差异无统计学意义(P>0.05);治疗后72 h,观察组患儿血清总胆红素水平(175.63±20.35)μmol/L明显低于对照组的(215.36±25.05)μmol/L,差异有统计学意义(P<0.05)。观察组患儿不良反应发生率5.41%低于对照组的24.32%,差异有统计学意义(P<0.05)。结论对新生儿黄疸患儿应用短时多次蓝光照射可以提高治疗效果,患儿血清总胆红素水平也在治疗后72 h快速下降,其不良反应发生率较低,是一种高效、可靠、安全的光疗方法,应该推广并普及。

Objective To investigate the clinical effect of short-term multiple blue light irradiation on neonatal jaundice.Methods A total of 74 cases of neonatal jaundice were divided into control group and observation group by random numerical table,with 37 cases in each group.Children in the control group received long-term continuous blue light irradiation treatment,and children in the observation group received short-term multiple blue light irradiation treatment.The therapeutic effects,incidence of adverse reactions after treatment,and serum total bilirubin levels before treatment and 48 and 72 h after treatment were compared between the two groups.Results The total effective rate of treatment in the observation group was 94.59%,which was higher than 78.38%in the control group,and the difference was statistically significant(P<0.05).Before treatment and 48 h after treatment,there was no statistically significant difference in serum total bilirubin levels between the two groups(P>0.05).72 h after treatment,the serum total bilirubin(175.63±20.35)μmol/L of the observation group was significantly lower than(215.36±25.05)μmol/L of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 5.41%in the observation group was lower than 24.32%in the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of neonatal jaundice,the use of short-term multiple blue light irradiation therapy can effectively improve the therapeutic effect,and the total serum bilirubin level of the children also decreases rapidly 72 h after treatment,with a low incidence of adverse effects,which is an efficient,reliable and safe phototherapy method and should be promoted and popularized.