摘要
目的:评价医院抗菌药物临床应用管理质量,为医院抗菌药物管理决策提供参考。方法:从医院信息系统中获取2012—2020年复旦大学附属肿瘤医院(以下简称"我院")抗菌药物管理质量评价相关指标,选取患者抗菌药物使用率、使用强度、Ⅰ类切口手术围手术期预防用药和治疗性用药的微生物送检率等10项指标,创建分析矩阵。利用熵权和逼近理想解排序法(TOPSIS)计算每年的相对接近程度(C_(i)),对管理质量进行综合评价。结果:基于熵权TOPSIS法,2012—2020年的Ci在0.218 8~0.760 2范围内;2012年的Ci为0.218 8,医院抗菌药物管理质量最差;2020年的Ci为0.760 2,医院抗菌药物管理质量最好;2013年、2017年和2018年是医院抗菌药物管理质量提升较快的3年;2017—2020年,医院抗菌药物管理质量持续提高。结论:我院抗菌药物临床应用管理质量整体呈现改善趋势。熵权TOPSIS法可以客观、全面地评价抗菌药物管理质量,为医院抗菌药物管理工作决策和方案制定提供参考。
OBJECTIVE: To evaluate the management quality of clinical application of antibiotics in hospitals,and to provide reference for decision-making of antimicrobial stewardship in hospitals. METHODS: Indicators related to the quality evaluation of antimicrobial stewardship in Fudan University Shanghai Cancer Center( hereinafter referred to as“our hospital”) from 2012 to 2020 were extracted from the hospital information system. Ten indicators were selected for analysis matrix,including the antimicrobial use rate,antibiotics use density,perioperative prophylactic medication for type Ⅰ incision surgery and microbiological detection rate of therapeutic drugs. Entropy weight-technique for order preference by similarity to ideal solution( TOPSIS) method was used to calculate the relative proximity( Ci) of each year for the comprehensive evaluation of management quality. RESULTS: Based on entropy weight-TOPSIS method,the Ci from 2012 to 2020 ranged from 0. 218 8 to 0. 760 2. The Ci in 2012 was 0. 218 8,indicating the worst quality of antimicrobial stewardship in our hospital. The Ci in 2020 was 0. 760 2,indicating the best quality of antimicrobial stewardship in our hospital. 2013,2017 and 2018 were three years of rapid improvement in the quality of antimicrobial stewardship in our hospital. From 2017 to 2020,the quality of antimicrobial stewardship in our hospital was improved.CONCLUSIONS: The quality of antimicrobial stewardship in our hospital shows an overall trend of improvement. The entropy-weighted TOPSIS method can objectively and comprehensively evaluate the quality of antimicrobial stewardship, and provide reference for hospital decision-making and program development of antimicrobial stewardship.
作者
张树敬
张燕
胡晓文
高宇
王清江
盛伟琪
ZHANG Shujing;ZHANG Yan;HU Xiaowen;GAO Yu;WANG Qingjiang;SHENG Weiqi(Dept.of Infection Control,Fudan University Shanghai Cancer Center,College of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China;Dept.of Pharmacy,Fudan University Shanghai Cancer Center,College of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China;Dept.of Information Center,Fudan University Shanghai Cancer Center,College of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China;Dept.of Medical Affair,Fudan University Shanghai Cancer Center,College of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China)
出处
《中国医院用药评价与分析》
2021年第12期1520-1523,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
2019年上海市卫生健康委员会面上项目(No.201940017)。
