乳腺肿瘤整形保乳术对早期乳腺癌患者术后乳房形态及预后的影响观察

Effects of Oncoplastic Breast-conserving Surgery on Postoperative Breast Morphology and Prognosis in Patients with Early Breast Cancer

目的:观察乳腺肿瘤整形保乳术(OBCS)对早期乳腺癌患者术后乳房形态及预后的影响。方法:选取2018年10月-2021年3月在本院接受治疗的62例早期乳腺癌患者,利用随机法分成OBCS组和非OBCS组,各31例。OBCS组采用OBCS外科治疗,非OBCS采用常规标准化乳腺肿瘤切除保乳术治疗。记录两组围术期指标(手术时间、术中出血量、术中引流量、住院时间),统计两组术后3个月美观度,对比术前、术后3个月两组生活质量[患者报告结局测量工具(BREAST-Q)、健康调查简表(SF-36)]水平,记录两组术后6个月内并发症发生情况与预后情况。结果:OBCS组手术时间、术中出血量、术中引流量、住院时间均显著少于非OBCS组(P<0.05)。术后3个月,两组SF-36评分均高于术前,且OBCS组均高于非OBCS组(P<0.05);OBCS组美观度优良例数、BREAST-Q得分均高于非OBCS组(P<0.05)。两组术后6个月内并发症、远处转移、复发情况比较,差异均无统计学意义(P>0.05)。结论:乳腺肿瘤整形保乳术对早期乳腺癌患者有较好的临床效果,具有提高患者乳房美感、改善生活质量的优势,适用于临床治疗。

Objective:To observe the effects of oncoplastic breast-conserving surgery (OBCS) on postoperative breast morphology and prognosis in patients with early breast cancer.Method:A total of 62 patients with early breast cancer treated in our hospital from October 2018 and March 2021 were selected,and they were divided into OBCS group and non-OBCS group according to the random method,31 cases in each group.OBCS group was given OBCS surgical treatment,and non-OBCS group was treated with conventional standardized breast cancer resection and breast-conserving surgery.The perioperative indicators (surgical time,intraoperative blood loss,intraoperative drainage volume,hospital stay) were recorded in two groups,and the aesthetic degree of two groups was statistically analyzed at 3 months after surgery.The quality of life[patient reported outcome measures (BREAST-Q),SF-36]were compared between two groups of patients before surgery and at 3 months after surgery.The complications and prognosis in two groups were recorded within 6 months after surgery.Result:The surgical time,intraoperative blood loss,intraoperative drainage volume and hospital stay in OBCS group were significantly less than those in non-OBCS group (P<0.05).At 3 months after surgery,the scores of SF-36 in two groups were significantly higher than those before surgery,and OBCS group were significantly higher than those in non-OBCS group (P<0.05);the total number of patients with excellent and good aesthetic degree and BREAST-Q score in OBCS group were significantly higher than those in non-OBCS group (P<0.05).There were no statistical differences in complications,distant metastasis and recurrence between two groups within 6 months after surgery (P>0.05).Conclusion:OBCS has a good clinical effect on patients with early breast cancer,and has the advantages of enhancing the breast aesthetics and improving the quality of life of patients,therefore it is suitable for clinical treatment.