摘要
目的:比较不同浓度右美托咪定在全膝关节置换术(TKA)连续收肌管阻滞中的应用效果。方法:将2020年8月-2021年8月厦门大学附属福州第二医院收治的160例TKA患者随机分成对照组(n=80)和研究组(n=80),对照组应用0.5μg/mL右美托咪定,研究组应用1.0μg/mL右美托咪定,两组均联合罗哌卡因进行连续收肌管阻滞麻醉。分析比较两组的术后疼痛、镇痛情况、股四头肌分级、不良反应发生情况。结果:研究组术后6、12、24、48 h VAS评分均低于对照组(P<0.05);镇痛泵按压、补救镇痛次数少于对照组(P<0.05);两组术后48 h的股四头肌分级比较,差异无统计学意义(P>0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:1.0μg/mL右美托咪定在TKA连续收肌管阻滞中的应用效果较好,可减轻患者术后疼痛,提高镇痛效果,值得推广。
Objective:To compare the effects of different concentrations of Dexmedetomidine in continuous adductor block in total knee arthroplasty(TKA).Method:A total of 160 patients with TKA treated in Fuzhou Second Hospital Affiliated to Xiamen University from August 2020 to August 2021 were randomly divided into control group(n=80)and study group(n=80).The control group was treated with 0.5μg/mL Dexmedetomidine,the study group was treated with 1.0μg/mL Dexmedetomidine,both groups were combined with Ropivacaine for continuous adductor block anesthesia.The postoperative pain,analgesia,quadriceps femoris grading and adverse reactions were analyzed and compared.Result:The VAS scores at 6,12,24 and 48 h after operation in the study group were lower than those of the control group(P<0.05);the times of analgesic pump pressing and remedial analgesia were lower than those of the control group(P<0.05);there was no significant difference in quadriceps femoris grading between the two groups at 48 h after operation(P>0.05);there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:1.0μg/mL Dexmedetomidine has a good effect in continuous adductor tube block in TKA operation.It can reduce postoperative pain and improve analgesic effect,it is worth popularizing.
作者
陈燕
王冰焱
CHEN Yan;WANG Bingyan(Fuzhou Second Hospital Affiliated to Xiamen University,Fuzhou 350007,China;不详)
出处
《中国医学创新》
CAS
2022年第1期45-48,共4页
Medical Innovation of China
关键词
不同浓度
右美托咪定
TKA手术
连续收肌管阻滞
Different concentrations
Dexmedetomidine
TKA surgery
Continuous adductor block