乳腺癌患者术后抑郁症状发生的相关危险因素分析

Analysis of Related Risk Factors of Postoperative Depressive Symptoms in Breast Cancer Patients

目的:分析乳腺癌患者术后抑郁症状发生的相关危险因素。方法:回顾性分析赣州市人民医院于2018年2月-2020年4月接诊的乳腺癌88例的临床资料。所有患者均行手术治疗,按术后是否发生抑郁分为抑郁组(n=54)和非抑郁组(n=34)。分析乳腺癌患者术后抑郁症状发生的相关危险因素。结果:88例乳腺癌患者术后发生抑郁54例(61.36%)。抑郁组年龄≤50岁、乳腺癌家族史、医疗自费、肿瘤分期Ⅲ和Ⅳ期、家庭月收入≤5000元、化疗周期≥5个比例均高于非抑郁组,差异均有统计学意义(P<0.05)。年龄≤50岁、乳腺癌家族史、医疗自费、肿瘤分期Ⅲ和Ⅳ期、家庭月收入≤5000元、化疗周期≥5个均为乳腺癌患者术后发生抑郁症状的高危因素(OR>1,P<0.05)。结论:乳腺癌患者术后抑郁症状发生与多种因素密切相关,临床需针对各高危因素制定针对性干预措施,以预防抑郁发生。

Objective:To analyze the risk factors of postoperative depressive symptoms in breast cancer patients.Method:The clinical data of 88 cases of breast cancer admitted in Ganzhou People’s Hospital from February 2018 to April 2020 were retrospectively analyzed.All patients underwent surgery,and were divided into depression group(n=54)and non-depression group(n=34)according to the occurrence of postoperative depression.The risk factors related to postoperative depression symptoms in breast cancer patients were analyzed.Result:Postoperative depression occurred in 54 cases(61.36%)of 88 breast cancer patients.The proportions of age≤50 years,family history of breast cancer,medical expenses,tumor stageⅢandⅣ,monthly family income≤5000 yuan,chemotherapy cycle≥5 in depressed group were higher than those in non-depressed group,and the differences were statistically significant(P<0.05).Age≤50 years,family history of breast cancer,medical expenses,tumor stageⅢandⅣ,monthly family income≤5000 yuan,chemotherapy cycle≥5 were the risk factors for postoperative depressive symptoms in breast cancer patients(OR>1,P<0.05).Conclusion:The occurrence of postoperative depressive symptoms in breast cancer patients is closely related to a variety of factors.Clinically,targeted intervention measures should be formulated for each high-risk factor to prevent depression.