膝骨性关节炎采用关节镜关节腔清理术后活血化瘀药物超声导入治疗价值研究

Value of Ultrasound-introduction of Drugs for Promoting Blood Circulation and Removing Blood Stasis after Arthroscopic Articular Cavity Debridement for Knee Osteoarthritis

目的:探究膝骨性关节炎(KOA)采用关节镜关节腔清理术后活血化瘀药物超声导入治疗的临床效果。方法:选取2018年12月-2020年12月阳江市中医医院收治的60例KOA患者,采用抛硬币法将其分为对照组和观察组,每组30例。两组均开展关节镜关节腔清理术治疗,对照组术后未采用其他治疗,观察组术后采用活血化瘀药物超声导入治疗。比较两组治疗效果,比较两组治疗前后疼痛、机体功能评分及血清炎性因子水平[白细胞介素-1β(IL-1β)与肿瘤坏死因子-α(TNF-α)]。结果:观察组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组VAS、机体功能评分比较,差异均无统计学意义(P>0.05);治疗后,两组VAS、机体功能评分均低于治疗前,且观察组机体功能评分低于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组VAS评分低于对照组,差异无统计学意义(P>0.05)。治疗前,两组IL-1β、TNF-α水平比较,差异均无统计学意义(P>0.05);治疗后,两组IL-1β、TNF-α水平均低于治疗前,且观察组均低于对照组,差异均有统计学意义(P<0.05)。结论:KOA患者采用关节镜关节腔清理术后活血化瘀药物超声导入治疗效果显著,可有效降低术后疼痛,改善膝关节功能及血清炎性因子水平。

Objective:To explore the clinical effect of ultrasound-introduction of drugs for promoting blood circulation and removing blood stasis after arthroscopic articular cavity debridement for knee osteoarthritis (KOA).Method:A total of 60 KOA patients admitted to Yangjiang Traditional Chinese Medicine Hospital from December 2018 to December 2020 were selected,they were divided into control group and observation group according to coin flipping method,30 cases in each group.Both groups were treated with arthroscopic articular cavity debridement,the control group received no other treatment after surgery,and the observation group was treated with ultrasound-introduction of drugs promoting blood circulation and removing blood stasis after surgery.The treatment effect were compared between two groups,and the pain,body function scores and serum inflammatory factors[interleukin-1β (IL-1β) and tumor necrosis factor-α(TNF-α)]before and after treatment were compared between two groups.Result:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant (P<0.05).Before treatment,there were no significant differences in VAS and WOMAC scores between two groups (P>0.05);after treatment,VAS and body function scores of both groups were lower than those before treatment,and body function scores of the observation group were lower than that of the control group,the differences were statistically significant (P<0.05).After treatment,VAS score of the observation group was lower than that of the control group,but the difference was not statistically significant (P>0.05).Before treatment,there were no significant differences in the levels of IL-1β and TNF-α between two groups (P>0.05);after treatment,the levels of IL-1β and TNF-α of both groups were lower than those before treatment,and those of the observation group were lower than those of the control group,the differences were statistically significant (P<0.05).Conclusion:The treatment of KOA patients with ultrasound-introduction of drugs for promoting blood circulation and removing blood stasis after arthroscopic articular cavity debridement can effectively reducing postoperative pain,improving knee joint function and serum inflammatory factor levels.