基于复杂网络分析《承淡安伤寒论新注》穴-症关系

Analysis of acupoint-symptom relationship in CHENG Dan-an’s Note About Treatise on Cold-Attack based on complex network

针对《承淡安伤寒论新注》有关针灸学的注解内容,提取穴位名称、主治病症等信息,基于复杂网络分析《承淡安伤寒论新注》穴-症关系,为使用复杂网络技术促进针灸现代化提供思路和方法。共纳入201条针灸处方,涉及112个腧穴,腧穴出现总频次为880次,形成42034个穴位配伍对。就网络指标而言,与基于相同数学方法建模研究的《经络腧穴学》《针灸大成》《针灸甲乙经》3部综合性针灸专著形成的复杂网络相比,《承淡安伤寒论新注》的模型具备更加典型的"小世界效应",表现为网络密度(6.762)更高,平均路径长度(1.064)更短,而这或与此书中舌脉等症状元素增加了穴位间的联系有关。节点指标中,对佩奇排名等拓扑学指标的分析则体现了以大椎为代表的穴位在针灸治疗外感病时具备更高的配伍价值,进一步论证了特征向量中心度指导智能化穴位配伍的临床价值。

Acupoint-symptom relationship in CHENG Dan-an’s Note About Treatise on Cold-Attack was analyzed based on complex network,acupoint names and indications were extracted from the book,which provided ideas and methods for promoting the modernization of acupuncture and moxibustion by using complex network technology.A total of 112 acupoints in 201 acupuncture prescriptions were included,and the total frequency of acupoints was 880 times,forming 42034 acupoint pairs.In terms of network indexes,compared with the complex network of comprehensive acupuncture books,such as Meridian and Acupoint Science,Zhenjiu Dacheng,Acupuncture A and B Meridians formed based on the same mathematical method,the complex network model for CHENG Dan-an’s Note About Treatise on Cold-Attack shows more typical small world effect,which is characterized by higher network density(6.762)and shorter average path length(1.064).This phenomenon may be related to the tongue and pulse which added the link between acupoints.For the node indexes,the analysis of topological indexes such as Page Rank shows that acupoints represented by Dazhui(GV 14)has higher compatibility value in the treatment of exogenous diseases,which further demonstrates the clinical value of eigenvector centrality in guiding intelligent compatibility of points.