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肠道微生物与肠上皮细胞互作关系的研究进展 被引量:2

Research Progress on Interactions between Intestinal Microbiota and Intestinal Epithelial Cells
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摘要 肠上皮细胞是动物机体抵抗细菌、病毒等有毒有害物质侵入黏膜下层的第一道屏障,由肠上皮细胞所介导的肠道微生物-上皮细胞-免疫细胞的互作对于维持肠道健康具有重要作用。本文综述了肠道微生物与肠上皮细胞之间的互作关系及其机制,旨在为益生菌调控动物肠道健康提供理论依据。 Intestinal epithelial cells behave the first barrier of intestinal bacteria,viruses and other toxic and harmful substances invasion into the submucosa of animals.The interactions among microbiota and epithelial cells and immune cells mediated by intestinal epithelial cells play an important role on intestinal health.This article reviews the interaction between intestinal microbiota and intestinal epithelial cells,and the underlying mechanism with the aim to provide theoretical basis for the application of probiotics for animal intestinal health.
作者 林玥莹 王敏奇 LIN Yueying;WANG Minqi(Key Laboratory of Molecular Animal Nutrition(Zhejiang University),Ministry of Education,China,College of Animal Science,Zhejiang University,Zhejiang Hangzhou 310058,China)
出处 《中国畜牧杂志》 CAS 北大核心 2021年第12期37-41,46,共6页 Chinese Journal of Animal Science
基金 国家重点研发计划项目(2018YFE0112700) 浙江省重点研发计划项目(2019C02005)。
关键词 肠道微生物 肠上皮细胞 益生菌 肠道稳态 Intestinal microbiota Intestinal epithelial cells Probiotics Intestinal homeostasis
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