血清CA125、CA153、CA72-4联合MSCT三期增强扫描对卵巢癌术前诊断价值分析

Preoperative Diagnostic Value of Serum CA125,CA153,and CA72-4 Combined with MSCT Three-Phase Enhanced Scan for Ovarian Cancer

目的分析血清CA125、CA153、CA72-4联合MSCT三期增强扫描对卵巢癌术前诊断价值。方法回顾性分析本院2018年11月至2019年9月收治的90例卵巢癌患者的临床资料。比较经血清CA125、CA153、CA72-4检查、MSCT检查以及四种联合检查对卵巢癌的准确性、敏感性、特异性。结果血清CA125对卵巢癌的诊断灵敏性、特异性和准确性分别为78.98%、75.56%、76.67%,血清CA153分别为68.89%、71.11%、70.00%,血清CA72-4分别为75.56%、66.67%、71.11%,MSCT检查分别为81.11%、72.22%、78.89%;四种联合诊断分别为93.33%、88.89%、92.22%,明显高于单一的血清CA125、CA153、CA72-4及MSCT检查(P<0.05)。结论经血清CA125、CA153、CA72-4及MSCT检查诊断卵巢癌均具有较高的价值,但四者联合可明显提高临床诊断价值,值得临床上广泛应用。

Objective To analyze the preoperative diagnostic value of serum CA125,CA153,and CA72-4 combined with MSCT three-phase enhanced scan for ovarian cancer.Methods The clinical data of 90 patients with ovarian cancer admitted to our hospital from November 2018 to September 2019 were retrospectively analyzed.The accuracy,sensitivity and specificity of serum CA125,CA153,CA72-4 examination,MSCT examination and four combined examinations for ovarian cancer were compared.Results The sensitivity,specificity and accuracy of serum CA125 for ovarian cancer were 78.98%,75.56%,and 76.67%,respectively.The serum CA153 were 68.89%,71.11%,and 70.00%,respectively.The serum CA72-4 were 75.56%,66.67%,and 71.11%,respectively.The MSCT examination were 81.11%,72.22%,and 78.89%,respectively.The four combined examinations were 93.33%,88.89%,and 92.22%,respectively,which were significantly higher than those of the single serum CA125,CA153,CA72-4,and MSCT examination(P<0.05).Conclusion Serum CA125,CA153,CA72-4,and MSCT have high value in the diagnosis of ovarian cancer,but the combination of four can significantly improve the clinical diagnostic value and is worthy of clinical application.