87例早孕期绒毛膜隆起的超声特征和妊娠结局分析

Analysis of the ultrasonic characteristics and pregnancy outcomes of 87 cases of chorionic bumps in early pregnancy

目的探讨早孕期绒毛膜隆起对妊娠结局的影响。方法回顾性分析在该院进行早孕期超声检查的孕妇43136例,其中绒毛膜隆起病例87例,纳入绒毛膜隆起组,其余早孕期孕妇,剔除多胎妊娠和辅助生殖妊娠,抽取650例纳入对照组。分析比较两组孕妇超声图像,对比两组孕妇早孕停育率与后续妊娠结局;将绒毛膜隆起组以病灶直径小于10 mm和大于或等于10 mm为标准分组,比较两组病例的妊娠结局。结果绒毛膜隆起发生率为0.20%。87例绒毛膜隆起病例,早孕期停育17例(19.50%),46例绒毛膜隆起继续妊娠后续自然流产5例,占10.87%,与对照组比较差异均有统计学意义(P<0.05);绒毛膜隆起组的胎儿畸形发生率与对照组相比较,差异无统计学意义(P>0.05);绒毛膜隆起病灶的大小与早孕期停育和后续妊娠结局无相关性,差异均无统计学意义(P>0.05)。结论绒毛膜隆起的发生率极低,可能是妊娠流产的危险因素,超声检查为绒毛膜隆起的诊断提供了重要的影像学依据。

Objective To investigate the effect of chorionic bump in early pregnancy on pregnancy outcome.Methods A total of 43136 pregnant women who underwent ultrasound examination during early pregnancy in a hospital were included in the retrospective analysis,including 87 cases of chorionic bump divided into the chorionic bump group.A total of 650 pregnant women in the remaining early pregnancy cases were randomly selected and divided into the early pregnancy control group after excluding multiple pregnancy and assisted reproductive pregnancy.The ultrasonic images of the two groups were analyzed to compare the difference of the early pregnancy termination rate and subsequent pregnancy outcome between the two groups.According to the diameter of the focus,the chorionic bump group was divided into two groups:<10 mm group and≥10 mm group.The pregnancy outcomes of the two groups were compared.Results The incidence of chorionic bump in the early pregnant women was about 0.20%.There were 87 cases of chorionic bump,and 17 cases had early pregnancy termination(19.54%).There were 46 cases of chorionic bump continuing pregnancy,and five cases had subsequent spontaneous abortion(10.87%).Compared with those of the control group in early pregnancy,the above differences were statistically significant(P<0.05).There was no significant difference in the incidence of fetal malformation between the chorionic bump group and the early pregnancy control group(P>0.05).There were no correlation between the size of the chorionic bump focus and the termination of early pregnancy/subsequent pregnancy outcome.The differences were not statistically significant(P>0.05).Conclusion The incidence of the chorionic bump is extremely low,which may be a risk factor for the pregnancy miscarriage.The ultrasonography provides important imaging evidence for the diagnosis of chorionic bump.