经尿道前列腺等离子剜除术治疗伴有经直肠前列腺活检病史的良性前列腺增生患者的有效性和安全性

Efficacy and safety of transurethral plasmakinetic enucleation of prostate in the treatment of benign prostatic hyperplasia patients with a history of transrectal prostate biopsy

目的探究经尿道前列腺等离子剜除术(PKEP)治疗伴有经直肠前列腺活检(TRPB)病史的良性前列腺增生(BPH)患者的有效性和安全性。方法选取我院2018年1月至2020年12月收治的40例TRPB后进行PKEP的BPH患者作为观察组,选取同期我院40例PKEP术前未实施TRPB的BPH患者作为对照组;回顾性分析两组患者的临床资料。比较两组的手术指标、膀胱残余尿量(RUV)、最大尿流率(MFR)及并发症发生情况。结果观察组的手术时间长于对照组(P<0.05);且观察组中,PKEP术与TRPB间隔≥2周患者的手术时间短于<2周患者(P<0.05);两组的术中出血量、膀胱冲洗时间、尿管留置时间比较,差异无统计学意义(P>0.05)。术后3个月,两组的RUV低于术前,MFR高于术前(P<0.05)。两组的并发症总发生率比较,差异无统计学意义(P>0.05)。结论PKEP治疗伴有TRPB病史的BPH患者安全可行,PKEP术与TRPB间隔2周及以上能够降低手术难度,缩短手术时间。

Objective To explore the efficacy and safety of transurethral plasmakinetic enucleation of prostate(PKEP)in the treatment of benign prostatic hyperplasia(BPH)patients with a history of transrectal prostate biopsy(TRPB).Methods A total of 40 BPH patients with PKEP after TRPB admitted in our hospital from January 2018 to December 2020 were selected as observation group,and 40 BPH patients without TRPB before PKEP in our hospital in the same period were selected as control group;the clinical data of patients in the two groups were analyzed retrospectively.The operative indexes,residual urinary volume(RUV),maximum urinary flow rate(MFR)and complications were compared between the two groups.Results The operation time in the observation group was longer than that in the control group(P<0.05);and in the observation group,the operation time in patients with an interval of≥2 weeks between PKEP and TRPB was shorter than that in patients with an interval of<2 weeks(P<0.05);there were no significant differences in the intraoperative bleeding,bladder flushing time and urinary catheter retention time between the two groups(P>0.05).Three months after operation,the RUV of the two groups was lower than that before operation,and the MFR was higher than that before operation(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion PKEP in the treatment of BPH patients with a history of TRPB is safe and feasible.The interval between PKEP and TRPB of 2 weeks or more can reduce the difficulty of operation and shorten the operation time.