摘要
棕榈酰乙醇胺(palmitoylethanolamide,PEA)是脂肪酸乙醇酰胺家族成员之一,具有调节房水流出通道、抑制炎性反应、调节视神经血供等作用,可能通过降低眼压、改善视神经血供和神经保护作用成为青光眼治疗的一个新途径。
Palmitoylethanolamide(PEA)is a member of fatty acid ethanolamide(FAE)family.At present,PEA has been proved to reduce intraocular pressure,regulate blood supply of optic nerve and neuroprotective effects,and may become a new approach for the treatment of glaucoma.PEA may treat glaucoma by regulating aqueous outflow channel,inhibiting inflammatory response,regulating blood supply to optic nerve and protecting optic nerve.
作者
唐丽颖
谢婷玉
张谋鑫
刘祖国
Tang Liying;Xie Tingyu;Zhang Mouxin;Liu Zuguo(Eye Institute of Xiamen University,Xiamen 361022,China;Department of Ophthalmology,Zhongshan Hosipital of Xiamen University,Xiamen 361004,China;Affiliated Xiamen Eye Center of Xiamen University,Xiamen 361004,China)
出处
《国际眼科纵览》
2021年第6期471-476,共6页
International Review of Ophthalmology
基金
国家重点研发计划(2018YFA0107304)
国家自然科学基金(81870627)
中央高校基本科研基金(20720202013)。
关键词
棕榈酰基乙醇胺
青光眼
眼压
神经保护
N-palmitoylethanolamide
glaucoma
intraocular pressure
nerve protection
