磺化聚醚醚酮负载银纳米颗粒抑菌膜制备及性能

Preparation and Performance of Sulfonated Polyetherether Ketone Loaded Silver Nanoparticles Antibacterial Membrane

用浓硫酸将聚醚醚酮(PEEK)材料磺化后作为基膜材料,将银纳米颗粒(AgNPs)嵌合到膜材料中合成SPEEK-AgNPs抑菌膜。用傅里叶变换红外色谱仪、扫描电子显微镜、原子力显微镜及X射线等方法分析该膜的表征,通过Ag+释放实验测试其安全性,并采用抗菌膜实验和悬浮抗菌实验测定其抗菌性。结果表明,磺化改性后的SPEEK材料与AgNPs结合良好,负载率较高,AgNPs在膜上平均尺寸为10~105 nm。在不同的释放条件下,SPEEK-AgNPs膜的Ag^(+)释放量总体上维持在安全浓度范围内。SPEEK-AgNPs膜可以有效抑制大肠杆菌、铜绿假单胞菌及金黄色葡萄球菌,其抑菌率高达95%以上。制取的SPEEK-AgNPs可以在安全的前提下较好的预防微生物污染,有良好的应用前景。

Polyetheretherketone(PEEK)material was sulfonated with concentrated sulfuric acid as the base membrane material,and silver nanoparticles(AgNPs)were embedded into the membrane material to synthesize SPEEK-AgNPs antibacterial membrane.The characterization of the film was analyzed by Fourier infrared spectroscopy,scanning electron microscopy,atomic force microscopy and X-ray.Its safety was tested by Ag^(+)release experiment,and its antibacterial activity was determined by antibacterial film experiment and suspension antibacterial experiment.The results show that the sulfonated SPEEK material is well combined with AgNPs,the loading rate is high,and the average size of AgNPs on the film is 10~105 nm.Under different release conditions,the Ag+release of SPEEK-AgNPs membrane is generally maintained in the safe concentration range.SPEEK-AgNPs membrane can effectively inhibit escherichia coli,pseudomonas aeruginosa and staphylococcus aureus,and its antibacterial rate is up to 95%or more.In conclusion,SPEEK-AgNPs prepared can better prevent microbial pollution on the premise of safety,and has a good application prospect.