分析泌尿系结石腔镜碎石术后重症感染的有效治疗方案

Analysis of effective treatment options for severe infections after endoscopic lithotripsy of urinary calculi

目的探析泌尿系结石腔镜碎石术后重症感染的有效治疗方案。方法42例泌尿系结石腔镜碎石术后重症感染患者为研究对象,回顾性分析腔镜碎石术后控制感染的方法。分析患者的治疗效果,比较患者治疗前后的疼痛评分及临床相关指标(体温、C反应蛋白、心率)。结果42例患者经治疗后均康复出院。停止补液时间为(16.67±4.59)h,血常规恢复正常时间为(4.25±1.30)d,体温恢复正常时间为(3.02±0.54)h,住院时间为(9.66±3.69)d,留置双J管者拔管时间为(25.14±3.31)d。治疗后,患者结石清除率为78.57%(33/42)。患者治疗后的疼痛评分(2.25±0.53)分低于治疗前的(7.40±1.30)分,差异具有统计学意义(P<0.05)。患者治疗后的体温(36.01±1.22)℃、C反应蛋白(90.30±8.31)mg/L、心率(95.10±2.01)次/min均低于治疗前的(38.50±1.47)℃、(113.20±15.29)mg/L、(109.01±5.01)次/min,差异具有统计学意义(P<0.05)。结论泌尿系结石腔镜碎石术后重症感染患者需及时给予针对性的治疗措施以及预后干预,有利于改善其疼痛、感染情况。

Objective To discuss the effective treatment options for severe infections after endoscopic lithotripsy of urinary calculi.Methods 42 patients with severe infection after endoscopic lithotripsy of urinary calculi were studied,and the methods of infection control after endoscopic lithotripsy were retrospectively analyzed.The therapeutic effects of patients were analyzed,and their pain scores and clinically relevant indexes(body temperature,C-reactive protein,heart rate)before and after treatment were compared.Results All 42 patients recovered and were discharged after treatment.The stop rehydration time was(16.67±4.59)h,the time to return to normal blood status was(4.25±1.30)d,body temperature recovery time was(3.02±0.54)h,the hospitalization time was(9.66±3.69)d,and the extubation time of indwelling double-J tubes was(25.14±3.31)d.After treatment,the stone clearance rate was 78.57%(33/42).After treatment,the pain score(2.25±0.53)points was lower than(7.40±1.30)points before treatment,and the difference was statistically significant(P<0.05).After treatment,the body temperature(36.01±1.22)℃,C-reactive protein(90.30±8.31)mg/L,and heart rate(95.10±2.01)beats/min were all lower than(38.50±1.47)℃,(113.20±15.29)mg/L,(109.01±5.01)times/min before treatment,and the difference was statistically significant(P<0.05).Conclusion Timely and targeted therapeutic measures and prognostic intervention are needed to improve the pain and infection of patients with severe infection after endoscopic lithotripsy of urinary calculi.