中西医结合治疗小儿轮状病毒肠炎的临床疗效观察

Clinical Effect of Combined Chinese and Western Medicine on Rotavirus Enteritis in Children

目的分析探讨临床接诊轮状病毒肠炎患儿在治疗过程中开展联合治疗(中医结合西医)对患儿病情的影响。方法研究共抽取650例轮状病毒肠炎病例,来源时间为2018年1月至2020年1月,获得患儿完整资料后进行分析。分组方式结合实际开展治疗方式分为对照组(n=325,常规西医治疗)与观察组(n=325,中医结合西医),分析对比两组患儿经不同给药方式治疗前后生活质量、症状改善、血清IL-6与TNF-α以及治疗后起效时间。结果①分析两组患儿经不同给药方式干预前后生活质量改善情况:干预后观察组各项评分均高于对照组,两组患者对比有统计学差异(P<0.05);②对比两组患儿经不同给药方式治疗前后症状改善情况:治疗后与对照组比较,观察组发热症状、呕吐症状以及脱水症状评分均更低,两组患者对比有统计学差异(P<0.05);③对比两组患儿经不同给药方式治疗前后血清变化情况:治疗后与对照组比较,观察组IL-6和TNF-α均偏低,两组患者对比有统计学差异(P<0.05)。结论临床接诊轮状病毒肠炎患儿在治疗过程中开展联合治疗(中医结合西医)对患儿病情影响显著,能确保患儿各项症状显著改善,同时还能缩短临床症状恢复时间,提升患儿生活质量,降低炎性因子水平。

Objective To analyze the effect of combined treatment(TCM combined with Western Medicine)on the patients with rotavirus enteritis.Methods Six hundred and fifty cases of rotavirus enteritis were selected from January 2018 to January 2020.The data of the children were analyzed.The treatment methods were divided into control group(n=325,conventional Western Medicine)and observation group(n=325,TCM combined with Western Medicine).The quality of life,symptom improvement,serum IL-6 and TNF-αand the effective time after treatment were analyzed and compared between the two groups.Results①The improvement of quality of life of the two groups before and after different administration methods were analyzed.The scores of the observation group were higher than those in the control group,and the difference between the two groups was statistically significant(P<0.05);②The results showed that the scores of fever,vomiting and dehydration were lower in the observation group compared with the control group,and the difference was statistically significant between the two groups(P<0.05);③The serum changes of the two groups were compared before and after different administration:Compared with the control group,the IL-6 and TNF-αin the observation group were lower than those in the control group,and there was statistical difference between the two groups(P<0.05).Conclusion The combination therapy(TCM combined with Western Medicine)has a significant effect on the condition of children with rotavirus enteritis,which can ensure the improvement of symptoms,shorten the recovery time of clinical symptoms,improve the quality of life and reduce the level of inflammatory factors.