2012—2020年重庆市女性乳腺癌发病率与死亡率变化趋势分析

Trends of Incidence and Mortality of Female Breast Cancer from 2012 to 2020 in Chongqing

[目的]分析2012—2020年重庆市女性乳腺癌发病率与死亡率及变化趋势。[方法]收集整理2012—2020年重庆市肿瘤登记点乳腺癌发病与死亡个案资料,采用SPSS 25.0统计分析发病率、中标发病率、死亡率、中标死亡率、年龄别发病率与死亡率等指标。不同地区女性乳腺癌发病率与死亡率的比较采用U检验,趋势分析采用SPSS 25.0曲线回归分析年度变化百分比(annual percentage change,APC)。[结果]重庆市女性乳腺癌发病率由2012年的21.66/10万上升至34.06/10万,APC为3.56%,变化趋势有统计学意义(P<0.05)。2012年与2020年乳腺癌中标发病率分别为21.67/10万与23.97/10万,APC为0.70%,变化趋势无统计学意义(P>0.05)。历年城市地区女性乳腺癌发病率均高于农村地区,差异均有统计学意义(P<0.05)。农村地区女性乳腺癌发病率以年均6.08%的速度上升,变化趋势有统计学意义(P<0.05)。50~59岁年龄组乳腺癌发病率以年均2.94%的速度上升,变化趋势有统计学意义(t=3.068,P=0.018)。2012年重庆市女性乳腺癌死亡率与中标死亡率分别为6.89/10万、4.87/10万,2020年分别为6.51/10万、3.91/10万,APC分别为-0.10%与-1.39%,变化趋势无统计学意义(P均>0.05)。城市地区女性乳腺癌标化死亡率以年均3.73%的速度下降,变化趋势有统计学意义(P<0.05)。30~39岁年龄组乳腺癌死亡率以年均7.04%的速度下降,变化趋势有统计学意义(P<0.05)。[结论]重庆市女性乳腺癌发病与死亡相对保持平稳。农村地区发病率上升趋势明显,是女性乳腺癌防治的重点。

[Purpose]To analyze the trends of incidence and mortality of female breast cancer in Chongqing from 2012 to 2020.[Methods]Data of new cases and death cases of female breast cancer from 2012 to 2020 in Chongqing were collected.The incidence,age-standardized incidence by Chinese standard population in 2000(ASIRC),mortality,age-standardized mortality by Chinese standard population in 2000(ASMRC),age specific incidence and mortality of female breast cancer were analyzed by SPSS 25.0.The incidence and mortality of female breast cancer in different areas were compared by U test.Annual percentage change(APC)of female breast cancer was analyzed by curve regression model of SPSS 25.0.[Results]The crude incidence of female breast cancer increased from 21.66/105 in 2012 to 34.06/105 in 2020 with an APC of 3.56%(P<0.05);while the ASIRC were 21.67/105 and 23.97/105 in 2012 and 2020,respectively with an APC of 0.70%(P>0.05).The incidence of female breast cancer in urban areas was higher than that in rural areas every year(P<0.05).The incidence of female breast cancer in rural areas increased by 6.08%from2012 to 2020.The incidence of female breast cancer in age group 50~59 years old increased by2.94%(t=3.068,P=0.018).The crude mortality rate and ASMRC of female breast cancer in 2012 were6.89/105 and 4.87/105;and those in 2020 were 6.51/105 and 3.91/105 with an APC of-0.10%and-1.39%,respectively.The ASMRC of female breast cancer in urban areas decreased by 3.73%annually(P<0.05).The ASMRC of female breast cancer in age group of 30~39 years decreased by7.04%annually(P<0.05).[Conclusion]The incidence and mortality of female breast cancer remained stable in Chongqing from 2012 to 2020.The incidence of female breast cancer in rural areas increased significantly,which should be the focus of cancer prevention and control.