初诊Ⅳ期乳腺癌原发灶局部区域治疗进展

Progress on Locoregional Therapy for Primary Tumors in De Novo Metastatic Breast Cancer

初诊Ⅳ期乳腺癌(de novo metastatic breast cancer,dnMBC)的生存结局非常差,其治疗方式以全身治疗为主。原发肿瘤的局部区域治疗被认为是姑息治疗的一种,通常被用来减轻肿瘤负荷。近期多项研究表明局部区域治疗可以改善初诊Ⅳ期乳腺癌患者的生存。全文对初诊Ⅳ期乳腺癌原发肿瘤局部区域治疗方式(手术或放疗)及其结果进行综述。

de novo metastatic breast cancer(dn MBC) has a poor survival outcome, and systemic treatment is its main treatment. Locoregional therapy of the primary tumor is considered as a form of palliative care, which is often used to reduce the tumor burden. However, several recent studies have shown that locoregional therapy can improve survival in dn MBC patients. In this paper, we reviewed the locoregional therapy methods for dn MBC, including surgical treatment for primary tumors and radiotherapy for primary tumors.