磁控胶囊内镜在体检人群小肠病变筛查中的应用

Using magnetic-controlled capsule endoscopy for small intestine screening in physical examination population

目的探讨磁控胶囊内镜在健康体检人群小肠疾病筛查中的应用价值。方法回顾分析解放军总医院健康管理研究院胃肠镜中心2019年1至12月期间行磁控胶囊内镜胃和小肠检查的1230例体检者的临床资料,分为有消化道症状组和无消化道症状组,统计分析体检者磁控胶囊内镜检查的完成情况及对体检者小肠病变的检出情况,并分析小肠病变与消化道症状的关系。结果体检者年龄为(54.4±17.3)岁,检查成功率为99.43%。30.09%(368/1230)的健康体检者检出各种不同性质的小肠病变;不同性别、有无症状对胶囊内镜通过小肠时间无影响;<50岁年龄组胶囊内镜通过小肠时间[(242.9±88.7)min]明显短于≥50岁年龄组[(336.4±112.1)min](P<0.05)。有症状组十二指肠球溃疡及十二指肠球炎检出率分别为1.73%(11/635)及6.14%(39/635),显著高于无症状组检出率0.17%(1/595)及2.02%(20/595)(P<0.05)。但两组小肠阳性病变检出率差异无统计学意义。结论小肠疾病在体检人群中有一定发生率,磁控胶囊内镜在完成胃检查的同时可以有效完成小肠疾病的筛查和诊断,是体检人群小肠疾病早期诊断和预防的有效工具。

Objective To investigate the application value of magnetic-controlled capsule endoscopy(MCE)for small intestine disease screening in physical examination population.Methods Physical examination data of 1230 individuals who received MCE examination from January to December 2019 in institute of Health Management were collected and retrospectively analyzed,and then divided into the gastrointestinal symptoms group and the group without gastrointestinal symptoms.Statistical analysis included the completion rate of MCE,the detection rate for small intestine disease in two groups,the relation between the gastrointestinal symptoms and small intestine diseases.Results The mean age of the subjects was(54.4±17.3)years.The success rate of completion was 99.43%,and the detection rate of intestine diseases was 30.09%(368/1230).Different genders and symptoms had no effect on the passage time of MCE through the small intestines,but the passage time of MCE through the small intestines in the age group younger than 50 years old[(242.9±88.7)min]was significantly less than in the age group greater than or equal to 50 years old[(336.4±112.1)min](P<0.05).The detection rate of a duodenal bulbal ulcer and duodenitis was 1.73%(11/635)and 6.14%(39/635)respectively,in the symptomatic group,which were significantly higher than in the asymptomatic group 0.17%(1/595)及2.02%(20/595)(P<0.05).However,there was no significant difference in the detection rate of positive lesions between the two groups.Conclusion There is a certain incidence of small intestinal diseases in people undergoing physical examinations.Magnetic-controlled capsule endoscopy can effectively complete the screening and diagnosis of small intestinal diseases while completing stomach examination,which is an effective tool for early diagnosis and prevention of small intestinal diseases in people undergoing physical examinations.