凉血消疕丸联合阿维A胶囊治疗掌跖脓疱病临床观察

Clinical Observation on the Treatment of Palmoplantar Pustulosis with Liangxue Xiaobi Pills Combined with Acitretin Capsule

目的:探讨凉血消疕丸与阿维A胶囊联合使用治疗掌跖脓疱病的临床疗效。方法:52名掌跖脓疱病患者通过采用随机数字表法划分为对照组和治疗组各26例。对照组患者仅服用阿维A胶囊剂,治疗组加服凉血消疕丸。治疗周期设定为8周,比较分析治疗后的两组皮损评分、总有效率、复发率及不良反应发生率。结果:结束治疗后观察,总有效率情况为治疗组92.3%,对照组80.8%,差异对比有统计学意义(P<0.05);治疗组治疗后的皮损评分及复发率均低于对照组,两组相比较,差异具有统计学意义(P<0.05)。结论:凉血消疕丸和阿维A胶囊联合使用治疗掌跖脓疱病较仅使用阿维A胶囊具有疗效优势,值得推广应用于掌跖脓疱病的临床治疗。

Objective:To probe the clinical efficacy of Liangxue Xiaobi Pills combined with Acitretin Capsule in the treatment of palmoplantar pustulosis.Methods:52 patients with palmoplantar pustulosis were divided into the control group and the treatment group by using the random number table method,each with 26 patients.The control group only took Acitretin Capsule,while the treatment group took Liangxue Xiaobi Pills with Acitretin Capsule.The treatment period was 8 weeks.After 8 weeks,the skin lesion score,clinical efficacy,untoward effect rate and recurrence rate were contrast with the two groups.Results:After treatment,the total effective rate was 92.3%in the treatment group and 80.8%in the control group,and the difference was statistically significant(χ^(2)=7.920,P<0.05).The skin lesion score and recurrence rate in the treatment group were obviously lower than those in the control group(P<0.05).The difference was statistically significant(χ^(2)=-2.466,P<0.05).Conclusion:The curative effect of Liangxue Xiaobi Pills combined with Acitretin Capsule in the treatment of palmoplantar pustulosis has a good effect on that who eat Acitretin Capsule alone,which is worthy of clinical application and popularization.