多囊卵巢综合征超声学血流动力诊断及其与性激素水平关系

Relationship between the ultrasonic diagnosis of women with polycystic ovary syndrome and their hormonal levels

目的:分析多囊卵巢综合征(PCOS)患者超声学诊断与性激素水平关系。方法:选择桐乡市妇幼保健院2018年12月-2020年12月治疗的PCOS患者50例作为观察组,同期体检健康女性50例为对照组,均行彩色多普勒超声检查及性激素检测并比较,Pearson分析超声学指标与性激素水平相关性。结果:观察组子宫阻力指数(RI)与对照组无差异,子宫搏动指数(PI)、卵巢体积(V)、卵泡数(FN)均高于对照组,卵巢RI、卵巢PI均低于对照组;观察组泌乳素(PRL)、孕酮(P)、雌二醇(E_(2))与对照组无差异,促黄体生成素(LH)、睾酮(T)均高于对照组,卵泡刺激素(FSH)低于对照组(均P<0.05)。子宫PI、RI、V、FN与PRL、P、E_(2)、LH、T、FSH呈正相关性,卵巢RI、PI与PRL、P、E_(2)、LH、T呈负相关性,卵巢RI、PI与FSH呈正相关性(均P<0.05)。结论:PCOS患者超声学指标与性激素水平存在一定相关性,提示临床加强上述指标检测,对PCOS的诊断和治疗具有临床意义。

Objective:To analyze the relationship between the ultrasonic diagnosis of women with polycystic ovary syndrome(PCOS)and their hormonal levels.Methods:50 women with PCOS were selected in observation group from December 2018 to December 2020,and 50 healthy women who received outpatient physical examination were selected in control group during the same period.Color Doppler ultrasound examinations were performed and compared in the women between the two groups and the sex hormone levels of the women were also detected and compared between the two groups.Pearson analysis was used to study the correlation between the ultrasound results of the women and their sex hormone levels.Results:There was no significant difference in the uterine resistance index(RI)value of the women between the two groups.The values of the uterine beating index(PI),ovarian volume(V),and follicle number(FN)of the women in the observation group were significantly higher than those of the women in the control group,while the ovarian RI and PI value of the women in the observation group were significantly lower.There were no significant differences in the levels of prolactin(PRL),progesterone(P),estradiol(E_(2)),luteinizing hormone(LH),testosterone(T),and follicle stimulating hormone(FSH)of the women between the two groups(all P<0.05).The value of uterine PI,RI,V,or FN of the women was positively correlated with their level of PRL,P,E_(2),LH,T,or FSH.The value of ovarian RI or PI of the women was negatively correlated with their level of PRL,P,E_(2),LH,or T.The value of ovarian RI or PI was positively correlated with their level of FSH(all P<0.05).Conclusion:There is a certain correlation between the ultrasound indexes of the women with PCOS and their sex hormone levels.It is suggested that strengthening the detection of the sex hormone levels of the women with PCOS and their examination of ultrasound indexes has clinical significance for the diagnosis and treatment of PCOS.