福州市社区居民不同类型肥胖与正常高值血压的关联性

The correlation between obesity phenotypes and high normal blood pressure in Fuzhou community residents

目的探讨福州社区居民不同类型肥胖与正常高值血压的相关性。方法采用横断面研究,以2018-2019年福州市仓山区、马尾区、连江县三地社区年龄>18岁常住人口作为研究对象,进行现场问卷调查、体格检查及实验室检查,纳入其中正常血压900人和正常高值血压1006人进行分析。采用多因素logistic回归模型分析不同类型肥胖与正常高值血压的相关性,并绘制受试者工作特征(ROC)曲线,分析不同性别人群中各类型肥胖对正常高值血压的预测能力。结果正常高值血压人群超重肥胖率、腹型肥胖率(28.4%比16.0%,χ^(2)=41.041,P<0.001)及腰围与身高比值(腰高比)异常率(61.6%比41.1%,χ^(2)=75.829,P<0.001)均高于正常血压组。多因素logistic回归分析显示,体质量指数(BMI)、腰围及腰高比与正常高值血压发生风险相关,其中超重(OR=1.896,95%CI 1.390~2.587)、肥胖(OR=2.489,95%CI 1.427~4.342)、腹型肥胖(OR=1.598,95%CI 1.152~2.215)及腰高比异常(OR=2.110,95%CI 1.579~2.821)是女性人群患正常高值血压的危险因素,腹型肥胖(OR=1.649,95%CI 1.021~2.661)及腰高比异常(OR=1.504,95%CI 1.044~2.165)是男性人群患正常高值血压的危险因素。ROC曲线结果显示,各类型肥胖的曲线下面积(AUC)均>0.6。结论超重、肥胖、腹型肥胖及腰高比异常是正常高值血压发生的危险因素。

Objective To explore the correlation between obesity phenotypes and high normal blood pressure among residents residing in Fuzhou communities.Methods A cross-sectional study was conducted and on-site questionnaire survey,physical examinations and laboratory tests were carried out on the residents aged over 18years in the communities of Cangshan District,Mawei District and Lianjiang County in Fuzhou city from 2018to 2019,in which 900people with normal blood pressure and 1006people with normal high blood pressure were included for analysis.Univariate analysis and multivariate logistic regression model were utilized to analyze the relationship between obesity phenotypes and high normal blood pressure.Receiver operating characteristic(ROC)curve was used to analyze the predictive power of various obesity phenotypes for high normal blood pressure in different genders.Results The rates of overweight and obesity,abdominal obesity(28.4%vs 16.0%,χ^(2)=41.041,P<0.001)and abnormal waist-to-height ratio(61.6%vs 41.1%,χ^(2)=75.829,P<0.001)in high normal blood pressure group were higher than those in normal blood pressure group.Multivariate logistic regression analysis showed that high normal blood pressure was positively correlated with body mass index(BMI),waist circumference and waist-to-height ratio.Furthermore,overweight(OR=1.896,95%CI 1.390-2.587),obesity(OR=2.489,95%CI 1.427-4.342),ab-dominal obesity(OR=1.598,95%CI 1.152-2.215)and abnormal waist-to-height ratio(OR=2.110,95%CI 1.579-2.821)were risk factors of high normal blood pressure among females while abdominal obesity(OR=1.649,95%CI 1.021-2.661)and abnormal waist-to-height ratio(OR=1.504,95%CI 1.044-2.165)were risk factors of high normal blood pressure among males.ROC curve showed that the areas under the curve(AUC)of all types of obesity were over 0.6.Conclusion Overweight,obesity,abdominal obesity and abnormal waist-to-height ratio are risk factors of high normal blood pressure.