山羊传染性胸膜肺炎研究进展

Research progress of contagious caprine pleuropneumonia

山羊传染性胸膜肺炎(CCPP)是一种由山羊支原体山羊肺炎亚种引起的严重疾病,偶有绵羊和野生反刍动物感染,具有超高的发病率和病死率。CCPP的病理特征为病变肺呈葡萄酒色,可完全肝化,通常伴随纤维素性胸膜炎,胸腔积聚大量积液。CCPP可通过血清学试验、DNA扩增(PCR、RFLP、杂交)和测序进行诊断。目前,抗生素疗法是CCPP的主要治疗方式,但长期使用抗生素易产生抗药性。文章针对不同时期提出的诊断方法和治疗措施进行梳理总结,以期为CCPP的防控和治疗提供参考与新思路。

Contagious caprine pleuropneumonia(CCPP) is a serious disease caused by Mycoplasma capricolum subsp.Capripneumoniae subspecies goat pneumonia, with occasionally infectes with sheep and wild ruminants and has an extremely high morbidity and fatality rate. The wine-colored diseased lung is the pathological feature of CCPP, can be completely hepatic,usually with fibrinous pleurisy, a large amount of fluid accumulates in the pleural cavity. CCPP can be diagnosed by serological tests, DNA amplification(PCR, RFLP, hybridization) and sequencing. At present, antibiotic therapy is the main treatment for CCPP, but long-term use of antibiotics is prone to drug resistance. The article sorts out and summarizes the diagnostic methods and treatment measures proposed in different periods, in order to provide reference and new ideas for prevention, control and treatment of CCPP.