摘要
为分析颈动脉中血液流动对内皮层的力学作用特性,本文通过建立颈动脉音叉型模型,基于流固耦合、第四弹性理论和柯西公式的方法研究了颈动脉"结构→力学"作用机制。发现颈动脉中的内皮层结构主要受到血液流动产生的压力和剪切力作用;音叉型颈动脉模型中的弯曲、分叉和直径突变结构使得颈动脉内的流体分布存在区域性紊流和较高的畸变能密度。可见紊流导致了低剪切应力的产生,而较高的畸变能密度说明血压是导致内皮层结构损伤的主要力学因素。
In order to analyze the mechanical characteristics of the carotid blood flow in the endothelium,a tuning fork model of carotid artery was established,and the fluid-solid coupling,fourth elastic theory and Cauchy formulawas used to investigatehe"structure-mechanics"mechanism of carotid artery in this paper.The results show that the endodermal structure of the carotid artery is mainly affected by the pressure and shear forces generated by blood flow.The bending,bifurcation and diameter mutation structures in the tuning fork model of carotid artery lead to regional turbulence and high distortion energy density in the fluid distribution in carotid artery.It is concluded that the turbulence leads to the generation of low shear stress,and the high distortion energy density indicates that blood pressure is the main mechanical factor leading to the damage of endodermal structure.
作者
陈若梦
席晓燕
张向红
韩忠义
高艳红
刘晓雯
CHEN Ruo-meng;XI Xiao-yan;ZHANG Xiang-hong;HAN Zhong-yi;GAO Yan-hong;LIU Xiao-wen(Key Lab of Intelligent Equipment Digital Design and Process Simulation,Tangshan University,Tangshan 063000,Hebei,China)
出处
《医学信息》
2022年第2期64-68,74,共6页
Journal of Medical Information
基金
河北省高层次人才资助项目(编号:A202001095)
唐山市科技计划项目(编号:20130225b)
唐山学院博士创新基金项目(编号:13100/1402001)。
关键词
颈动脉
内皮层
流固耦合
低剪切力
压力
Carotid artery
Endothelium
Fluid-structure coupling
Low shear force
Pressure